Biosensing with dnazymes

EM McConnell, I Cozma, Q Mou, JD Brennan… - Chemical Society …, 2021 - pubs.rsc.org
This article provides a comprehensive review of biosensing with DNAzymes, providing an
overview of different sensing applications while highlighting major progress and seminal …

Nucleic acid tests for clinical translation

M Li, F Yin, L Song, X Mao, F Li, C Fan, X Zuo… - Chemical …, 2021 - ACS Publications
Nucleic acids, including deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), are
natural biopolymers composed of nucleotides that store, transmit, and express genetic …

[HTML][HTML] Uranium in natural waters and the environment: Distribution, speciation and impact

PL Smedley, DG Kinniburgh - Applied Geochemistry, 2023 - Elsevier
The concentrations of U in natural waters are usually low, being typically less than 4 μg/L in
river water, around 3.3 μg/L in open seawater, and usually less than 5 μg/L in groundwater …

Self-protected DNAzyme walker with a circular bulging DNA shield for amplified imaging of miRNAs in living cells and mice

Y Gao, S Zhang, C Wu, Q Li, Z Shen, Y Lu, ZS Wu - ACS nano, 2021 - ACS Publications
Abnormal expression of miRNAs is often detected in various human cancers. DNAzyme
machines combined with gold nanoparticles (AuNPs) hold promise for detecting specific …

Metal sensing by DNA

W Zhou, R Saran, J Liu - Chemical reviews, 2017 - ACS Publications
Metal ions are essential to many chemical, biological, and environmental processes. In the
past two decades, many DNA-based metal sensors have emerged. While the main …

DNA nano-pocket for ultra-selective uranyl extraction from seawater

Y Yuan, T Liu, J **ao, Q Yu, L Feng, B Niu… - Nature …, 2020 - nature.com
Extraction of uranium from seawater is critical for the sustainable development of nuclear
energy. However, the currently available uranium adsorbents are hampered by co-existing …

Rationally engineered nucleic acid architectures for biosensing applications

M **ao, W Lai, T Man, B Chang, L Li… - Chemical …, 2019 - ACS Publications
Development of biosensing platforms plays a key role in research settings for identification
of biomarkers and in clinical applications for diagnostics. Biosensors based on nucleic acids …

Simultaneous Fe2+/Fe3+ imaging shows Fe3+ over Fe2+ enrichment in Alzheimer's disease mouse brain

Y Wu, SF Torabi, RJ Lake, S Hong, Z Yu, P Wu… - Science …, 2023 - science.org
Visualizing redox-active metal ions, such as Fe2+ and Fe3+ ions, are essential for
understanding their roles in biological processes and human diseases. Despite the …

DNAzymes as activity-based sensors for metal ions: recent applications, demonstrated advantages, current challenges, and future directions

RJ Lake, Z Yang, JJ Zhang, Y Lu - Accounts of chemical research, 2019 - ACS Publications
Conspectus Metal ions can be beneficial or toxic depending on their identity, oxidation state,
and concentration. Therefore, the ability to detect and quantify different types of metal ions …

Functional nucleic acid-based hydrogels for bioanalytical and biomedical applications

J Li, L Mo, CH Lu, T Fu, HH Yang, W Tan - Chemical Society Reviews, 2016 - pubs.rsc.org
Hydrogels are crosslinked hydrophilic polymers that can absorb a large amount of water. By
their hydrophilic, biocompatible and highly tunable nature, hydrogels can be tailored for …