Background To evaluate the effects of administering chemotherapy following surgery, or
following surgery plus radiotherapy (known as adjuvant chemotherapy) in patients with early …

Introduction A large number of trials have evaluated the efficacy of postoperative
chemotherapy on survival after resection for lung cancer, and a smaller number have …

Objective: To evaluate the effect of cytotoxic chemotherapy on survival in patients with non-
small cell lung cancer. Design: Meta-analysis using updated data on individual patients from …

BACKGROUND: Many randomised controlled trials have investigated the effect of adjuvant
chemotherapy in operable non-small-cell lung cancer. We undertook two comprehensive …

Background In a previous phase 3 trial of adjuvant chemotherapy after resection of non–
small-cell lung cancer, a combination of uracil and tegafur (often referred to as UFT) taken …

Study objectives Stage IIIA non-small cell lung cancer represents a relatively heterogeneous
group of patients with metastatic disease to the ipsilateral mediastinal (N2) lymph nodes and …

Purpose To determine the role of adjuvant chemotherapy and radiation therapy in patients
with completely resected stage IA-IIIA non–small-cell lung cancer (NSCLC). Methods The …

Background. Nonsmall cell lung cancer (NSCLC) has become the leading cause of cancer‐
related deaths in women and men in the United States, with more than 157,000 estimated …

BACKGROUND Angiogenesis in individuals with various solid tumors has provided useful
information on tumor progression and prognosis, and many examples of mast cell (MC) …

PURPOSE We performed a study to determine whether postoperative mild chemotherapy to
maintain the patient's quality of life (QOL) and immunoactivity could also prolong survival …