Extracellular pH impacts many molecular, cellular and physiological processes, and hence
is tightly regulated. Yet, in tumours, dysregulated cancer cell metabolism and poor vascular …

Transcatheter arterial chemoembolisation (TACE) is the standard of care for intermediate-
stage hepatocellular carcinoma and selected patients with advanced hepatocellular …

Simple Summary Immune checkpoint inhibitor (ICI) therapy has recently become the
standard treatment for advanced hepatocellular carcinoma (HCC); however, clinical …

Purpose To surmount the critical issues of indocyanine green (ICG), and thus achieving a
precise surgical navigation of primary liver cancer after long-term transcatheter arterial …

Background & Aims Metabolic reprogramming, in particular, glycolytic regulation, supports
abnormal survival and growth of hepatocellular carcinoma (HCC) and could serve as a …

Background The low extracellular pH (pH e) of tumors resulting from glycolytic metabolism is
a stress factor for the cells independent from concomitant hypoxia. The aim of the study was …

Glioblastoma progression involves multifaceted changes in vascularity, cellularity, and
metabolism. Capturing such complexities of the tumor niche, from the tumor core to the …

Purpose To demonstrate feasibility of develo** a noninvasive extracellular pH (pHe)
map** method on a clinical MRI scanner for molecular imaging of liver cancer. Methods In …

The management of hepatocellular carcinoma (HCC) is undergoing transformational
changes due to the emergence of various novel immunotherapies and their combination …

Hepatocellular carcinoma (HCC) is a tumor that exhibits glucometabolic reprogramming,
with a high incidence and poor prognosis. Usually, HCC is not discovered until an advanced …