Nanocomposite hydrogels: 3D polymer–nanoparticle synergies for on-demand drug delivery

S Merino, C Martín, K Kostarelos, M Prato, E Vázquez - ACS nano, 2015 - ACS Publications
Considerable progress in the synthesis and technology of hydrogels makes these materials
attractive structures for designing controlled-release drug delivery systems. In particular, this …

Stimulus-cleavable chemistry in the field of controlled drug delivery

Y Xue, H Bai, B Peng, B Fang, J Baell, L Li… - Chemical Society …, 2021 - pubs.rsc.org
Stimulus-cleavable nanoscale drug delivery systems are receiving significant attention
owing to their capability of achieving exquisite control over drug release via the exposure to …

Designing smart polymer conjugates for controlled release of payloads

F Seidi, R Jenjob, D Crespy - Chemical reviews, 2018 - ACS Publications
Incorporating labile bonds inside polymer backbone and side chains yields interesting
polymer materials that are responsive to change of environmental stimuli. Drugs can be …

[HTML][HTML] Hydrogels in drug delivery: Progress and challenges

TR Hoare, DS Kohane - polymer, 2008 - Elsevier
There has been considerable progress in recent years in addressing the clinical and
pharmacological limitations of hydrogels for drug delivery applications but substantial …

PEG hydrogels for the controlled release of biomolecules in regenerative medicine

CC Lin, KS Anseth - Pharmaceutical research, 2009 - Springer
Polyethylene glycol (PEG) hydrogels are widely used in a variety of biomedical applications,
including matrices for controlled release of biomolecules and scaffolds for regenerative …

Shear‐thinning supramolecular hydrogels with secondary autonomous covalent crosslinking to modulate viscoelastic properties in vivo

CB Rodell, JW MacArthur Jr, SM Dorsey… - Advanced functional …, 2015 - Wiley Online Library
Clinical percutaneous delivery of synthetically engineered hydrogels remains limited due to
challenges posed by crosslinking kinetics—too fast leads to delivery failure, too slow limits …

Michael addition reactions in macromolecular design for emerging technologies

BD Mather, K Viswanathan, KM Miller… - Progress in Polymer …, 2006 - Elsevier
The Michael addition reaction is a versatile synthetic methodology for the efficient coupling
of electron poor olefins with a vast array of nucleophiles. This review outlines the role of the …

Hydrolytically degradable poly (ethylene glycol) hydrogel scaffolds with tunable degradation and mechanical properties

SP Zustiak, JB Leach - Biomacromolecules, 2010 - ACS Publications
The objective of this work was to create 3D hydrogel matrices with defined mechanical
properties as well as tunable degradability for use in applications involving protein delivery …

Volumetric printing of thiol‐ene photo‐cross‐linkable poly (ε‐caprolactone): a tunable material platform serving biomedical applications

Q Thijssen, A Quaak, J Toombs… - Advanced …, 2023 - Wiley Online Library
Current thoroughly described biodegradable and cross‐linkable polymers mainly rely on
acrylate cross‐linking. However, despite the swift cross‐linking kinetics of acrylates, the …

Determination of the in vivo degradation mechanism of PEGDA hydrogels

MB Browning, SN Cereceres, PT Luong… - … Research Part A, 2014 - Wiley Online Library
Abstract Poly (ethylene glycol)(PEG) hydrogels are one of the most extensively utilized
biomaterials systems due to their established biocompatibility and highly tunable properties …