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Nanocomposite hydrogels: 3D polymer–nanoparticle synergies for on-demand drug delivery
Considerable progress in the synthesis and technology of hydrogels makes these materials
attractive structures for designing controlled-release drug delivery systems. In particular, this …
attractive structures for designing controlled-release drug delivery systems. In particular, this …
Stimulus-cleavable chemistry in the field of controlled drug delivery
Stimulus-cleavable nanoscale drug delivery systems are receiving significant attention
owing to their capability of achieving exquisite control over drug release via the exposure to …
owing to their capability of achieving exquisite control over drug release via the exposure to …
Designing smart polymer conjugates for controlled release of payloads
Incorporating labile bonds inside polymer backbone and side chains yields interesting
polymer materials that are responsive to change of environmental stimuli. Drugs can be …
polymer materials that are responsive to change of environmental stimuli. Drugs can be …
[HTML][HTML] Hydrogels in drug delivery: Progress and challenges
TR Hoare, DS Kohane - polymer, 2008 - Elsevier
There has been considerable progress in recent years in addressing the clinical and
pharmacological limitations of hydrogels for drug delivery applications but substantial …
pharmacological limitations of hydrogels for drug delivery applications but substantial …
PEG hydrogels for the controlled release of biomolecules in regenerative medicine
Polyethylene glycol (PEG) hydrogels are widely used in a variety of biomedical applications,
including matrices for controlled release of biomolecules and scaffolds for regenerative …
including matrices for controlled release of biomolecules and scaffolds for regenerative …
Shear‐thinning supramolecular hydrogels with secondary autonomous covalent crosslinking to modulate viscoelastic properties in vivo
CB Rodell, JW MacArthur Jr, SM Dorsey… - Advanced functional …, 2015 - Wiley Online Library
Clinical percutaneous delivery of synthetically engineered hydrogels remains limited due to
challenges posed by crosslinking kinetics—too fast leads to delivery failure, too slow limits …
challenges posed by crosslinking kinetics—too fast leads to delivery failure, too slow limits …
Michael addition reactions in macromolecular design for emerging technologies
The Michael addition reaction is a versatile synthetic methodology for the efficient coupling
of electron poor olefins with a vast array of nucleophiles. This review outlines the role of the …
of electron poor olefins with a vast array of nucleophiles. This review outlines the role of the …
Hydrolytically degradable poly (ethylene glycol) hydrogel scaffolds with tunable degradation and mechanical properties
The objective of this work was to create 3D hydrogel matrices with defined mechanical
properties as well as tunable degradability for use in applications involving protein delivery …
properties as well as tunable degradability for use in applications involving protein delivery …
Volumetric printing of thiol‐ene photo‐cross‐linkable poly (ε‐caprolactone): a tunable material platform serving biomedical applications
Current thoroughly described biodegradable and cross‐linkable polymers mainly rely on
acrylate cross‐linking. However, despite the swift cross‐linking kinetics of acrylates, the …
acrylate cross‐linking. However, despite the swift cross‐linking kinetics of acrylates, the …
Determination of the in vivo degradation mechanism of PEGDA hydrogels
MB Browning, SN Cereceres, PT Luong… - … Research Part A, 2014 - Wiley Online Library
Abstract Poly (ethylene glycol)(PEG) hydrogels are one of the most extensively utilized
biomaterials systems due to their established biocompatibility and highly tunable properties …
biomaterials systems due to their established biocompatibility and highly tunable properties …