Antibiotic-mediated perturbation of the gut microbiome is associated with numerous
infectious and autoimmune diseases of the gastrointestinal tract. Yet, as the gut microbiome …

Clostridium difficile epidemiology has changed in recent years, with the emergence of highly
virulent types associated with severe infections, high rates of recurrences and mortality …

Abstract Scope In 2009, the European Society of Clinical Microbiology and Infectious
Diseases (ESCMID) published the first treatment guidance document for Clostridioides …

Triptolide (TP), a traditional Chinese medicine, has been reported to be effective in the
treatment of autoimmune diseases and exerting antineoplastic activity in several human …

Summary Background The control of Clostridium difficile infections is an international clinical
challenge. The incidence of C difficile in England declined by roughly 80% after 2006 …

Since publication of the Society for Healthcare Epidemiology of America position paper on
Clostridium difficile infection in 1995, significant changes have occurred in the epidemiology …

Clostridium difficile is now considered to be one of the most important causes of health care-
associated infections. C. difficile infections are also emerging in the community and in …

The epidemiology of Clostridium difficile infection (CDI) has changed dramatically during
this millennium. Infection rates have increased markedly in most countries with detailed …

Background Recent reports suggest that the rate and severity of Clostridium difficile–
associated disease in the United States are increasing and that the increase may be …

Background In March 2003, several hospitals in Quebec, Canada, noted a marked increase
in the incidence of Clostridium difficile–associated diarrhea. Methods In 2004 we conducted …