The production of aromatic amino acids using fermentation processes with recombinant
microorganisms can be an advantageous approach to reach their global demands. In …

Analytical approaches for a comprehensive understanding of the metabolic networks in
microbial cultures are mostly based on small-scale cultures which are in a steady state or …

Background Glycerol has enhanced its biotechnological importance since it is a byproduct of
biodiesel synthesis. A study of Escherichia coli physiology during growth on glycerol was …

Advanced bioproduct synthesis via reductive metabolism requires coordinating carbons,
ATP and reducing agents, which are generated with varying efficiencies depending on …

For industrial strain construction, rational allocation of carbon flux is of paramount
importance especially for decoupling cell growth and chemical productions to get maximum …

In Escherichia coli, the phosphoenolpyruvate–carbohydrate phosphotransferase system
(PTS) is responsible for the transport and phosphorylation of sugars, such as glucose. PTS …

The aromatic class of chemicals includes a large number of industrially important products.
In bacteria and plants, the shikimate pathway and related biosynthetic pathways are a …

Abstract l-Tryptophan is an important aromatic amino acid that is used widely in the food,
chemical, and pharmaceutical industries. Compared with the traditional synthetic methods …

Escherichia coli is the best-known model for the biotechnological production of many
biotechnological products, including housekee** and heterologous primary and …

Background Shikimic acid (SA) is utilized in the synthesis of oseltamivir-phosphate, an anti-
influenza drug. In this work, metabolic engineering approaches were employed to produce …