Drug-resistant epilepsy: definition, pathophysiology, and management

B Mesraoua, F Brigo, S Lattanzi, B Abou-Khalil… - Journal of the …, 2023‏ - Elsevier
There are currently> 51 million people with epilepsy (PWE) in the world and every year> 4.9
million people develop new-onset epilepsy. The cornerstone of treatment in PWE is drug …

Magnetic resonance‐guided laser interstitial thermal therapy for drug‐resistant epilepsy: A systematic review and individual participant data meta‐analysis

JS Chen, AA Lamoureux, NA Shlobin, LM Elkaim… - …, 2023‏ - Wiley Online Library
Magnetic resonance‐guided laser interstitial thermal therapy (MRgLITT) has emerged as a
popular minimally invasive alternative to open resective surgery for drug‐resistant epilepsy …

Stereotactic MRI‐guided laser interstitial thermal therapy for extratemporal lobe epilepsy

K Gupta, B Cabaniss, A Kheder, S Gedela, P Koch… - …, 2020‏ - Wiley Online Library
Objective Magnetic resonance imaging (MRI)–guided laser interstitial thermal therapy (MRg‐
LITT) is an alternative to open epilepsy surgery. We assess safety and effectiveness of MRg …

Surgical outcomes between temporal, extratemporal epilepsies and hypothalamic hamartoma: systematic review and meta-analysis of MRI-guided laser interstitial …

N Barot, K Batra, J Zhang, ML Klem… - Journal of Neurology …, 2022‏ - jnnp.bmj.com
Background Approximately 1/3 of patients with epilepsy have drug-resistant epilepsy (DRE)
and require surgical interventions. This meta-analysis aimed to review the effectiveness of …

Robot-assisted, real-time, MRI-guided laser interstitial thermal therapy for pediatric patients with hypothalamic hamartoma: surgical technique, pitfalls, and initial …

S Candela-Cantó, J Muchart… - Journal of …, 2022‏ - thejns.org
OBJECTIVE Real-time, MRI-guided laser interstitial thermal therapy (MRgLITT) has been
reported as a safe and effective technique for the treatment of epileptogenic foci in children …

Minimally invasive procedures for hypothalamic hamartoma–related epilepsy: a systematic review and meta-analysis

A Iranmehr, MAD Ohadi, M Chavoshi… - Neurosurgical …, 2022‏ - thejns.org
OBJECTIVE Hypothalamic hamartoma (HH) is a rare, nonmalignant, heterotopic
developmental malformation that consists of a mixture of normal neurons and glial cells …

Current applications and safety profile of laser interstitial thermal therapy in the pediatric population: a systematic review of the literature

S Zeller, J Kaye, F Jumah, SS Mantri, J Mir… - Journal of …, 2021‏ - thejns.org
OBJECTIVE Laser interstitial thermal therapy (LITT) provides a minimally invasive
alternative to open brain surgery, making it a powerful neurosurgical tool especially in …

Direct resection is a safe and effective strategy to control seizures in patients with hypothalamic hamartoma

Y Ou, J Yuan, C Li - Scientific Reports, 2024‏ - nature.com
Achieving favorable seizure outcomes is challenging in patients with seizures resulting from
hypothalamic hamartoma. Although minimally invasive and non-invasive surgical …

Hypothalamic Hamartoma related epilepsy: A systematic review exploring clinical, neuropsychological, and psychiatric outcome after surgery

C Luisi, L Salimbene, N Pietrafusa, M Trivisano… - Epilepsy & Behavior, 2024‏ - Elsevier
The post-surgical outcome for Hypothalamic Hamartoma (HH) related epilepsy in terms of
seizure freedom (SF) has been extensively studied, while cognitive and psychiatric outcome …

Magnetic resonance-guided laser interstitial thermal therapy (MR-gLiTT) in pediatric epilepsy surgery: state of the art and presentation of Giannina Gaslini Children's …

A Consales, E Cognolato, M Pacetti… - Frontiers in …, 2021‏ - frontiersin.org
Magnetic resonance-guided laser interstitial thermal therapy (MR-gLiTT) is a novel
minimally invasive treatment approach for drug-resistant focal epilepsy and brain tumors …