A fractional-order model for optimizing combination therapy in heterogeneous lung cancer: integrating immunotherapy and targeted therapy to minimize side effects

D Amilo, C Izuchukwu, K Sadri, HR Yao, E Hincal… - Scientific Reports, 2024 - nature.com
This research presents a novel approach to address the complexities of heterogeneous lung
cancer dynamics through the development of a Fractional-Order Model. Focusing on the …

Advances in Precision Medicine Approaches for Colorectal Cancer: From Molecular Profiling to Targeted Therapies

NS Kiran, C Yashaswini, R Maheshwari… - ACS Pharmacology & …, 2024 - ACS Publications
Precision medicine is transforming colorectal cancer treatment through the integration of
advanced technologies and biomarkers, enhancing personalized and effective disease …

A fractional-order model for nosocomial infection caused by pseudomonas aeruginosa in Northern Cyprus

C Bagkur, D Amilo, B Kaymakamzade - Computers in Biology and Medicine, 2024 - Elsevier
Pseudomonas aeruginosa, a resilient gram-negative bacterium, poses a persistent threat as
a leading cause of nosocomial infections, particularly in resource-constrained regions …

[HTML][HTML] Stability and BI-RADS 4 subcategories mitigate on cancer risk dynamics with fractional operators: A case study analysis

M Farman, N Gokbulut, E Hincal, KS Nisar - Alexandria Engineering …, 2024 - Elsevier
In this paper, we present a mathematical model to lower the probability of breast cancer risk
of the Breast Imaging Reporting and Data Systems (BI-RADS) 4 subcategories with the …

An optimal solution for tumor growth model using generalized Bessel polynomials

H Saeidi, MS Dahaghin, S Mehrabi… - … Methods in the …, 2025 - Wiley Online Library
In this paper, a mathematical model is given that depicts the interactions between cancer
cells and viruses in the setting of oncolytic virotherapy. The model is separated into three …

[HTML][HTML] The impact of PTEN status on glioblastoma multiforme: A glial cell type-specific study identifies unique prognostic markers

AVSS Krishna, S Sinha, MRS Rao… - Computers in Biology and …, 2025 - Elsevier
Glioblastoma multiforme (GBM) is the most invasive form of brain tumor, accounting for 5%
of the cases per 100,000 people in various countries. The phosphatase and tensin homolog …

New insights into disease dynamics and treatment interventions with PID controller-based therapeutic strategies for pancreatic cancer

D Amilo, K Sadri, M Farman, E Hincal… - Computers & Mathematics …, 2025 - Elsevier
In this paper, we developed a mathematical model for pancreatic cancer progression using
a system of nonlinear partial differential equations (PDEs) with time delays, capturing …

Unknown-input pseudo-state observer synthesis for fractional-order systems: A geometric framework

HA Nozari, SJS Rostami, P Castaldi - Chaos, Solitons & Fractals, 2024 - Elsevier
This paper explores the development and characterization of the invariant subspaces in
geometric control theory, namely conditioned invariant, input-containing, unobservability …

2D scale-3 fractional Euler wavelets optimization algorithm for fractional-order differential equations

F Zhou, J Zhang - Journal of Computational Science, 2024 - Elsevier
A numerical scheme combining particle swarm optimization (PSO) optimization algorithm for
solving fractional-order differential equations is developed by using 2D scale-3 fractional …

A fractional-order model for the effects of expansions in hospitals on the applicability of performance certificate programme

B Kara, B Kaymakamzade, T Tulbentci… - … in Science and …, 2025 - Taylor & Francis
This study explores the impact of the Leadership in Energy and Environmental Design
(LEED) certification system on healthcare services in private hospitals in North Cyprus using …