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Chaperone-assisted cryo-EM structure of P. aeruginosa PhuR reveals molecular basis for heme binding
Pathogenic bacteria, such as Pseudomonas aeruginosa, depend on scavenging heme for
the acquisition of iron, an essential nutrient. The TonB-dependent transporter (TBDT) PhuR …
the acquisition of iron, an essential nutrient. The TonB-dependent transporter (TBDT) PhuR …
Resolving the conformational ensemble of a membrane protein by integrating small-angle scattering with AlphaFold
The function of a protein is enabled by its conformational landscape. For non-rigid proteins,
a complete characterization of this landscape requires understanding the protein's structure …
a complete characterization of this landscape requires understanding the protein's structure …