The use of RNA-based treatments in the field of cancer immunotherapy

M Chehelgerdi, M Chehelgerdi - Molecular Cancer, 2023 - Springer
Over the past several decades, mRNA vaccines have evolved from a theoretical concept to a
clinical reality. These vaccines offer several advantages over traditional vaccine techniques …

Microbiota medicine: towards clinical revolution

P Gebrayel, C Nicco, S Al Khodor, J Bilinski… - Journal of translational …, 2022 - Springer
The human gastrointestinal tract is inhabited by the largest microbial community within the
human body consisting of trillions of microbes called gut microbiota. The normal flora is the …

Microbiota triggers STING-type I IFN-dependent monocyte reprogramming of the tumor microenvironment

KC Lam, RE Araya, A Huang, Q Chen, M Di Modica… - Cell, 2021 - cell.com
The tumor microenvironment (TME) influences cancer progression and therapy response.
Therefore, understanding what regulates the TME immune compartment is vital. Here we …

Alterations of the gut microbiota in patients with coronavirus disease 2019 or H1N1 influenza

S Gu, Y Chen, Z Wu, Y Chen, H Gao… - Clinical Infectious …, 2020 - academic.oup.com
Abstract Background Coronavirus disease 2019 (COVID-19) is an emerging serious global
health problem. Gastrointestinal symptoms are common in COVID-19 patients, and severe …

Functional effects of human milk oligosaccharides (HMOs)

M Dinleyici, J Barbieur, EC Dinleyici, Y Vandenplas - Gut Microbes, 2023 - Taylor & Francis
Human milk oligosaccharides (HMOs) are the third most important solid component in
human milk and act in tandem with other bioactive components. Individual HMO levels and …

Control of lymphocyte functions by gut microbiota-derived short-chain fatty acids

CH Kim - Cellular & molecular immunology, 2021 - nature.com
A mounting body of evidence indicates that dietary fiber (DF) metabolites produced by
commensal bacteria play essential roles in balancing the immune system. DF, considered …

Potential intestinal infection and faecal–oral transmission of SARS-CoV-2

M Guo, W Tao, RA Flavell, S Zhu - Nature reviews Gastroenterology & …, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread to more than
200 countries and regions globally. SARS-CoV-2 is thought to spread mainly through …

The gut–airway microbiome axis in health and respiratory diseases

M Özçam, SV Lynch - Nature Reviews Microbiology, 2024 - nature.com
Communication between the gut and remote organs, such as the brain or the cardiovascular
system, has been well established and recent studies provide evidence for a potential …

Microbiota-derived acetate enhances host antiviral response via NLRP3

J Niu, M Cui, X Yang, J Li, Y Yao, Q Guo, A Lu… - Nature …, 2023 - nature.com
Pathogenic viral infections represent a major challenge to human health. Host immune
responses to respiratory viruses are closely associated with microbiome and metabolism via …

[HTML][HTML] The lung–gut axis during viral respiratory infections: the impact of gut dysbiosis on secondary disease outcomes

V Sencio, MG Machado, F Trottein - Mucosal Immunology, 2021 - Elsevier
Bacteria that colonize the human gastrointestinal tract are essential for good health. The gut
microbiota has a critical role in pulmonary immunity and host's defense against viral …