The genome of all organisms is spatially organized to function efficiently. The advent of
genome-wide chromatin conformation capture (Hi-C) methods has revolutionized our ability …

Highlights•Chromatin folding into topologically associated domains (TADs) is pervasive
across animal groups.•TADs are plastic entities composed of genomic strata from different …

The molecular mechanism underlying brain regeneration in vertebrates remains elusive. We
performed spatial enhanced resolution omics sequencing (Stereo-seq) to capture spatially …

Sensory neurons in the dorsal root ganglion (DRG) and trigeminal ganglion (TG) are
specialized to detect and transduce diverse environmental stimuli to the central nervous …

Antarctic krill (Euphausia superba) is Earth's most abundant wild animal, and its enormous
biomass is vital to the Southern Ocean ecosystem. Here, we report a 48.01-Gb chromosome …

Salamanders are tetrapod models to study brain organization and regeneration; however,
the identity and evolutionary conservation of brain cell types are largely unknown. We …

Chemoreception–the ability to smell and taste–is an essential sensory modality of most
animals. The number and type of chemical stimuli that animals can perceive depends …

Limb regeneration, while observed lifelong in salamanders, is restricted in post-
metamorphic Xenopus laevis frogs. Whether this loss is due to systemic factors or an …

Chromatids of mitotic chromosomes were suggested to coil into a helix in early cytological
studies and this assumption was recently supported by chromosome conformation capture …

Comparative genomics is the comparison of genetic information within and across
organisms to understand the evolution, structure, and function of genes, proteins, and non …