[HTML][HTML] Low dose ionizing radiation effects on the immune system

K Lumniczky, N Impens, G Armengol, S Candéias… - Environment …, 2021 - Elsevier
Ionizing radiation interacts with the immune system in many ways with a multiplicity that
mirrors the complexity of the immune system itself: namely the need to maintain a delicate …

Pathological effects of ionizing radiation: endothelial activation and dysfunction

B Baselet, P Sonveaux, S Baatout, A Aerts - Cellular and molecular life …, 2019 - Springer
The endothelium, a tissue that forms a single layer of cells lining various organs and cavities
of the body, especially the heart and blood as well as lymphatic vessels, plays a complex …

[HTML][HTML] Cardiovascular diseases related to ionizing radiation: The risk of low-dose exposure

B Baselet, C Rombouts… - International …, 2016 - spandidos-publications.com
Traditionally, non-cancer diseases are not considered as health risks following exposure to
low doses of ionizing radiation. Indeed, non-cancer diseases are classified as deterministic …

Modulation of inflammatory immune reactions by low-dose ionizing radiation: molecular mechanisms and clinical application

F Rodel, B Frey, U Gaipl, L Keilholz… - Current medicinal …, 2012 - ingentaconnect.com
During the last decade, a multitude of experimental evidence has accumulated showing that
low-dose radiation therapy (single dose 0.5-1 Gy) functionally modulates a variety of …

Understanding radiation-induced cardiovascular damage and strategies for intervention

FA Stewart, I Seemann, S Hoving, NS Russell - Clinical oncology, 2013 - Elsevier
There is a clear association between therapeutic doses of thoracic irradiation and an
increased risk of cardiovascular disease (CVD) in cancer survivors, although these effects …

Radiobiological mechanisms in inflammatory diseases of low-dose radiation therapy

F Rödel, L Keilholz, M Herrmann, R Sauer… - … journal of radiation …, 2007 - Taylor & Francis
Purpose: Whereas X-irradiation with high doses is established to exert pro-inflammatory
effects, low-dose radiotherapy (LD-RT) with single fractions below 1.0 Gy and a total dose …

Brain damage and patterns of neurovascular disorder after ionizing irradiation. Complications in radiotherapy and radiation combined injury

NV Gorbunov, JG Kiang - Radiation research, 2021 - meridian.allenpress.com
Exposure to ionizing radiation, mechanical trauma, toxic chemicals or infections, or
combinations thereof (ie, combined injury) can induce organic injury to brain tissues, the …

Radiation-induced immunity and toxicities: the versatility of the cGAS-STING pathway

J Constanzo, J Faget, C Ursino, C Badie… - Frontiers in …, 2021 - frontiersin.org
In the past decade, radiation therapy (RT) entered the era of personalized medicine,
following the striking improvements in radiation delivery and treatment planning …

Low and moderate doses of ionizing radiation up to 2 Gy modulate transmigration and chemotaxis of activated macrophages, provoke an anti-inflammatory cytokine …

R Wunderlich, A Ernst, F Rödel… - Clinical & …, 2015 - academic.oup.com
Benign painful and inflammatory diseases have been treated for decades with low/moderate
doses of ionizing radiation (LD-X-irradiation). Tissue macrophages regulate initiation and …

Contribution of the immune system to bystander and non-targeted effects of ionizing radiation

F Rödel, B Frey, G Multhoff, U Gaipl - Cancer letters, 2015 - Elsevier
Considerable progress has recently been achieved in the understanding of molecular
mechanisms involved in cellular radiation responses and radiation mediated …