The cellular and molecular mechanisms underpinning tissue repair and its failure to heal are
still poorly understood, and current therapies are limited. Poor wound healing after trauma …

Tissue engineering has become a promising strategy for repairing damaged cartilage and
bone tissue. Among the scaffolds for tissue-engineering applications, injectable hydrogels …

Mesenchymal stem cells (MSCs) have been extensively investigated for the treatment of
various diseases. The therapeutic potential of MSCs is attributed to complex cellular and …

Biomaterials have played an increasingly prominent role in the success of biomedical
devices and in the development of tissue engineering, which seeks to unlock the …

The extracellular matrix (ECM) is a fundamental component of multicellular organisms that
provides mechanical and chemical cues that orchestrate cellular and tissue organization …

Reconstruction of bone defects, especially the critical-sized defects, with mechanical
integrity to the skeleton is important for a patient's rehabilitation, however, it still remains …

Abstract Three-dimensional (3D) printing enables the production of anatomically matched
and patient-specific devices and constructs with high tunability and complexity. It also allows …

Pulp necrosis arrests root development in injured immature permanent teeth, which may
result in tooth loss. However, dental pulp regeneration and promotion of root development …

The field of stem cells and regenerative medicine offers considerable promise as a means of
delivering new treatments for a wide range of diseases. In order to maximize the …

Regenerative medicine holds the promise of engineering functional tissues or organs to
heal or replace abnormal and necrotic tissues/organs, offering hope for filling the gap …