Origin of intrinsic irregular firing in cortical interneurons

KM Stiefel, B Englitz, TJ Sejnowski - … of the National Academy of Sciences, 2013 - pnas.org
Cortical spike trains are highly irregular both during ongoing, spontaneous activity and when
driven at high firing rates. There is uncertainty about the source of this irregularity, ranging …

Phase descriptions of a multidimensional Ornstein-Uhlenbeck process

PJ Thomas, B Lindner - Physical Review E, 2019 - APS
Stochastic oscillators play a prominent role in different fields of science. Their simplified
description in terms of a phase has been advocated by different authors using distinct phase …

The voltage and spiking responses of subthreshold resonant neurons to structured and fluctuating inputs: persistence and loss of resonance and variability

RFO Pena, HG Rotstein - Biological cybernetics, 2022 - Springer
We systematically investigate the response of neurons to oscillatory currents and synaptic-
like inputs and we extend our investigation to non-structured synaptic-like spiking inputs with …

Thermodynamic formalism in neuronal dynamics and spike train statistics

R Cofré, C Maldonado, B Cessac - Entropy, 2020 - mdpi.com
The Thermodynamic Formalism provides a rigorous mathematical framework for studying
quantitative and qualitative aspects of dynamical systems. At its core, there is a variational …

Phase resetting in an asymptotically phaseless system: On the phase response of limit cycles verging on a heteroclinic orbit

KM Shaw, YM Park, HJ Chiel, PJ Thomas - SIAM Journal on Applied …, 2012 - SIAM
Rhythmic behaviors in neural systems often combine features of limit-cycle dynamics
(stability and periodicity) with features of near heteroclinic or near homoclinic cycle …

The sha** of intrinsic membrane potential oscillations: positive/negative feedback, ionic resonance/amplification, nonlinearities and time scales

HG Rotstein - Journal of computational neuroscience, 2017 - Springer
The generation of intrinsic subthreshold (membrane potential) oscillations (STOs) in
neuronal models requires the interaction between two processes: a relatively fast positive …

Membrane potential synchrony of neurons in anterior cingulate cortex plays a pivotal role in generation of neuropathic pain

Z Chen, X Shen, L Huang, H Wu, M Zhang - Scientific Reports, 2018 - nature.com
The pathophysiology of neuropathic pain generation has not been fully investigated.
Previous studies have primarily focused on changes in the properties of single neurons in …

Subthreshold oscillating waves in neural tissue propagate by volume conduction and generate interference

CC Chiang, DM Durand - Brain Sciences, 2022 - mdpi.com
Subthreshold neural oscillations have been observed in several brain regions and can
influence the timing of neural spikes. However, the spatial extent and function of these …

Neural coding of space by time

H Löffler, DS Gupta, A Bahmer - Biological Cybernetics, 2024 - Springer
The intertwining of space and time poses a significant scientific challenge, transcending
disciplines from philosophy and physics to neuroscience. Deciphering neural coding …

A lower bound for the first passage time density of the suprathreshold Ornstein-Uhlenbeck process

PJ Thomas - Journal of applied probability, 2011 - cambridge.org
We prove that the first passage time density ρ (t) for an Ornstein-Uhlenbeck process X (t)
obeying dX=-β Xdt+ σdW to reach a fixed threshold θ from a suprathreshold initial condition …