Significant experimental, computational, and theoretical work has identified rich structure
within the coordinated activity of interconnected neural populations. An emerging challenge …

In vivo two-photon calcium imaging (2PCI) is a technique used for recording neuronal
activity in the intact brain. It is based on the principle that, when neurons fire action …

INTRODUCTION Perceptual experiences in mammals may arise from patterns of neural
circuit activity in cerebral cortex. For example, primary visual cortex (V1) is causally capable …

Multiphoton microscopy can resolve fluorescent structures and dynamics deep in scattering
tissue and has transformed neural imaging, but applying this technique in vivo can be …

Two-photon imaging in behaving animals has revealed neuronal activities related to
behavioral and cognitive function at single-cell resolution. However, marmosets have posed …

Monkeys are a premier model organism for neuroscience research. Activity in the central
nervous systems of monkeys can be recorded and manipulated while they perform complex …

Modern optical neuroimaging approaches are expanding the ability to elucidate complex
brain function. Diverse imaging contrasts enable direct observation of neural activity with …

Calcium imaging is a powerful tool for recording from large populations of neurons in vivo.
Imaging in rhesus macaque motor cortex can enable the discovery of fundamental principles …

Optical imaging methods using calcium indicators are critical for monitoring the activity of
large neuronal populations in vivo. Imaging experiments typically generate a large amount …

Microendoscopic calcium imaging with one-photon miniature microscopes enables
unprecedented readout of neural circuit dynamics during active behavior in rodents. In this …