Possible chemical and physical scenarios towards biological homochirality

Q Sallembien, L Bouteiller, J Crassous… - Chemical Society …, 2022 - pubs.rsc.org
The single chirality of biological molecules in terrestrial biology raises more questions than
certitudes about its origin. The emergence of biological homochirality (BH) and its …

The search for chiral asymmetry as a potential biosignature in our solar system

DP Glavin, AS Burton, JE Elsila, JC Aponte… - Chemical …, 2019 - ACS Publications
The search for evidence of extraterrestrial life in our Solar System is currently guided by our
understanding of terrestrial biology and its associated biosignatures. The observed …

Identifying molecules as biosignatures with assembly theory and mass spectrometry

SM Marshall, C Mathis, E Carrick, G Keenan… - Nature …, 2021 - nature.com
The search for alien life is hard because we do not know what signatures are unique to life.
We show why complex molecules found in high abundance are universal biosignatures and …

Prebiotic systems chemistry: new perspectives for the origins of life

K Ruiz-Mirazo, C Briones, A de la Escosura - Chemical reviews, 2014 - ACS Publications
The origin of life is a fascinating, unresolved problem whose deciphering would have
important scientific, epistemological and social implications. Over time, philosophers and …

The ladder of life detection

M Neveu, LE Hays, MA Voytek, MH New, MD Schulte - Astrobiology, 2018 - liebertpub.com
We describe the history and features of the Ladder of Life Detection, a tool intended to guide
the design of investigations to detect microbial life within the practical constraints of robotic …

Asymmetric aminocatalysis—gold rush in organic chemistry

P Melchiorre, M Marigo, A Carlone… - Angewandte Chemie …, 2008 - Wiley Online Library
Catalysis with chiral secondary amines (asymmetric aminocatalysis) has become a well‐
established and powerful synthetic tool for the chemo‐and enantioselective functionalization …

Evolution of glutamatergic signaling and synapses

LL Moroz, MA Nikitin, PG Poličar, AB Kohn… - …, 2021 - Elsevier
Glutamate (Glu) is the primary excitatory transmitter in the mammalian brain. But, we know
little about the evolutionary history of this adaptation, including the selection of l-glutamate …

The origin of biological homochirality

DG Blackmond - Cold Spring Harbor perspectives in …, 2010 - cshperspectives.cshlp.org
The single-handedness of biological molecules has fascinated scientists and laymen alike
since Pasteur's first painstaking separation of the enantiomorphic crystals of a tartrate salt …

Meteorite-catalyzed syntheses of nucleosides and of other prebiotic compounds from formamide under proton irradiation

R Saladino, E Carota, G Botta… - Proceedings of the …, 2015 - National Acad Sciences
Liquid formamide has been irradiated by high-energy proton beams in the presence of
powdered meteorites, and the products of the catalyzed resulting syntheses were analyzed …

Biomimetic catalysis

L Marchetti, M Levine - ACS Catalysis, 2011 - ACS Publications
The field of biomimetic chemistry encompasses a wide variety of subfields, including
biomimetic catalysis, bioinspired self-assembly, and biomimetic reactions in total synthesis …