Approaches to revealing the neural basis of muscle synergies: a review and a critique

VCK Cheung, K Seki - Journal of neurophysiology, 2021 - journals.physiology.org
The central nervous system (CNS) may produce coordinated motor outputs via the
combination of motor modules representable as muscle synergies. Identification of muscle …

Muscle synergies for evaluating upper limb in clinical applications: A systematic review

K Zhao, Z Zhang, H Wen, B Liu, J Li, A d'Avella… - Heliyon, 2023 - cell.com
Introduction Muscle synergies have been proposed as a strategy employed by the central
nervous system to control movements. Muscle synergy analysis is a well-established …

Plasticity of muscle synergies through fractionation and merging during development and training of human runners

VCK Cheung, BMF Cheung, JH Zhang… - Nature …, 2020 - nature.com
Complex motor commands for human locomotion are generated through the combination of
motor modules representable as muscle synergies. Recent data have argued that muscle …

Challenging human locomotion: stability and modular organisation in unsteady conditions

A Santuz, A Ekizos, N Eckardt, A Kibele… - Scientific reports, 2018 - nature.com
The need to move over uneven terrain is a daily challenge. In order to face unexpected
perturbations due to changes in the morphology of the terrain, the central nervous system …

On the methodological implications of extracting muscle synergies from human locomotion

A Santuz, A Ekizos, L Janshen… - … journal of neural …, 2017 - World Scientific
We investigated the influence of three different high-pass (HP) and low-pass (LP) filtering
conditions and a Gaussian (GNMF) and inverse-Gaussian (IGNMF) non-negative matrix …

Modular control of human movement during running: an open access data set

A Santuz, A Ekizos, L Janshen, F Mersmann… - Frontiers in …, 2018 - frontiersin.org
The human body is an outstandingly complex machine including around 1000 muscles and
joints acting synergistically. Yet, the coordination of the enormous amount of degrees of …

Methodological choices in muscle synergy analysis impact differentiation of physiological characteristics following stroke

CL Banks, MM Pai, TE McGuirk, BJ Fregly… - Frontiers in …, 2017 - frontiersin.org
Muscle synergy analysis (MSA) is a mathematical technique that reduces the dimensionality
of electromyographic (EMG) data. Used increasingly in biomechanics research, MSA …

An objective, information-based approach for selecting the number of muscle synergies to be extracted via non-negative matrix factorization

S Ranaldi, C De Marchis, G Severini… - IEEE Transactions on …, 2021 - ieeexplore.ieee.org
Muscle synergy analysis is a useful tool for the evaluation of the motor control strategies and
for the quantification of motor performance. Among the parameters that can be extracted …

An optogenetic demonstration of motor modularity in the mammalian spinal cord

V Caggiano, VCK Cheung, E Bizzi - Scientific reports, 2016 - nature.com
Motor modules are neural entities hypothesized to be building blocks of movement
construction. How motor modules are underpinned by neural circuits has remained …

Muscle synergies in Parkinson's disease

I Mileti, A Zampogna, A Santuz, F Asci, Z Del Prete… - Sensors, 2020 - mdpi.com
Over the last two decades, experimental studies in humans and other vertebrates have
increasingly used muscle synergy analysis as a computational tool to examine the …