[HTML][HTML] Combined therapeutics: Future opportunities for co-therapy with thrombectomy

P Rajendram, A Ikram, M Fisher - Neurotherapeutics, 2023‏ - Elsevier
Stroke is an urgent public health issue with millions of patients worldwide living with its
devastating effects. The advent of thrombolysis and endovascular thrombectomy has …

Endovascular treatment for anterior circulation large-vessel occlusion ischemic stroke with low ASPECTS: a systematic review and meta-analysis

A Safouris, L Palaiodimou, I Szikora… - Therapeutic …, 2022‏ - journals.sagepub.com
Background: Endovascular treatment (EVT) for acute ischemic stroke (AIS) patients
presenting with Alberta Stroke Program Early CT Score (ASPECTS) 0–5 has not yet proven …

Safety and clinical outcomes of endovascular therapy versus medical management in late presentation of large ischemic stroke

A Mujanovic, D Strbian, J Demeestere… - European stroke …, 2024‏ - journals.sagepub.com
Introduction: The benefit of endovascular therapy (EVT) among stroke patients with large
ischemic core (ASPECTS 0–5) in the extended time window outside of trial settings remains …

Association of thrombectomy with functional outcome for patients with ischemic stroke who presented in the extended time window with extensive signs of infarction

G Broocks, U Hanning, M Bechstein… - JAMA Network …, 2022‏ - jamanetwork.com
Importance Only limited data are available about a potential benefit associated with
endovascular treatment (EVT) for patients with ischemic stroke presenting in the extended …

Endovascular Therapy and Outcomes Among Patients With Very Large Ischemic Core Stroke

D **e, J Huang, S Fan, C Guo, W Sun, Z Peng… - JAMA Network …, 2024‏ - jamanetwork.com
Importance The association of endovascular therapy (EVT) with outcomes is unclear for
patients with very low Alberta Stroke Program Early Computed Tomography Score …

Endovascular treatment versus standard medical treatment in patients with established large infarct: a cohort study

C Guo, L Li, J Huang, J Yang, J Song… - … Journal of Surgery, 2024‏ - journals.lww.com
Background: Previous trials confirmed the benefit of endovascular treatment (EVT) in acute
large core stroke, but the effect of EVT on outcomes in these patients based on noncontrast …

The feasibility of mechanical thrombectomy versus medical management for acute stroke with a large ischemic territory

A Aslan, S Abuzahra, N Adeeb, B Musmar… - Journal of …, 2025‏ - jnis.bmj.com
Background Mechanical thrombectomy (MT) for acute ischemic stroke is generally avoided
when the expected infarction is large (defined as an Alberta Stroke Program Early CT Score …

Assessment of irreversible tissue injury in extensive ischemic stroke—potential of quantitative cerebral perfusion

W Haupt, L Meyer, M Wagner, R McDonough… - Translational Stroke …, 2023‏ - Springer
Computed tomography perfusion (CTP) is used as a tool to select ischemic stroke patients
for endovascular treatment (EVT) and is currently investigated in the setting of extensive …

Timing and causes of death after endovascular thrombectomy in patients with acute ischemic stroke

WM Sluis, WH Hinsenveld… - European stroke …, 2023‏ - journals.sagepub.com
Introduction: Endovascular thrombectomy (EVT) increases the chance of good functional
outcome after ischemic stroke caused by a large vessel occlusion, but the risk of death in the …

Deep Learning–Based ASPECTS Algorithm Enhances Reader Performance and Reduces Interpretation Time

A Ayobi, A Davis, PD Chang, DS Chow, K Nael… - American Journal of …, 2025‏ - ajnr.org
ABSTRACT BACKGROUND AND PURPOSE: ASPECTS is a long-standing and well
documented selection criteria for acute ischemic stroke treatment, however, the …