Cu (I)-catalyzed click chemistry in glycoscience and their diverse applications

AK Agrahari, P Bose, MK Jaiswal, S Rajkhowa… - Chemical …, 2021‏ - ACS Publications
Copper (I)-catalyzed 1, 3-dipolar cycloaddition between organic azides and terminal
alkynes, commonly known as CuAAC or click chemistry, has been identified as one of the …

The clinical impact of glycobiology: targeting selectins, Siglecs and mammalian glycans

BAH Smith, CR Bertozzi - Nature Reviews Drug Discovery, 2021‏ - nature.com
Carbohydrates—namely glycans—decorate every cell in the human body and most secreted
proteins. Advances in genomics, glycoproteomics and tools from chemical biology have …

Glycan-lectin interactions powered biosensors for the instant screening of viruses and beyond

M Li, H Ji, Y Wang, C Zhang, X Zhang, Y Wu… - TrAC Trends in …, 2023‏ - Elsevier
Pathogenic viruses constitute a hazard factor to public hygiene. The usage of biosensors for
instant screening of viruses is becoming increasingly prevalent due to their ultrafast …

[HTML][HTML] Pharmaceutical advances: Integrating artificial intelligence in QSAR, combinatorial and green chemistry practices

B Singh, M Crasto, K Ravi, S Singh - Intelligent Pharmacy, 2024‏ - Elsevier
The utilization of pharmaceuticals in medical and veterinary treatment has not only improved
human and animal health but has also boosted food-production and economic welfare …

CarboGrove: a resource of glycan-binding specificities through analyzed glycan-array datasets from all platforms

ZL Klamer, CM Harris, JM Beirne, JE Kelly… - …, 2022‏ - academic.oup.com
Glycan arrays continue to be the primary resource for determining the glycan-binding
specificity of proteins. The volume and diversity of glycan-array data are increasing, but no …

VaporLIFT: On‐Chip Chemical Synthesis of Glycan Microarrays

A Tsouka, M Mende, J Heidepriem… - Advanced Functional …, 2024‏ - Wiley Online Library
Laser‐induced forward transfer (LIFT) of polymers is a versatile printing method for parallel
in situ synthesis of peptides on microarrays. Chemical building blocks embedded in a …

Multivalent glycocyclopeptides: conjugation methods and biological applications

D Goyard, AMS Ortiz, D Boturyn… - Chemical Society …, 2022‏ - pubs.rsc.org
Click chemistry was extensively used to decorate synthetic multivalent scaffolds with glycans
to mimic the cell surface glycocalyx and to develop applications in glycosciences …

Nanolayer laser absorber for femtoliter chemistry in polymer reactors

J Zhang, Y Liu, S Ronneberger, NV Tarakina… - Advanced …, 2022‏ - Wiley Online Library
Laser‐induced forward transfer (LIFT) has the potential to be an alternative approach to
atomic force microscopy based scanning probe lithography techniques, which have …

Laser-driven growth of structurally defined transition metal oxide nanocrystals on carbon nitride photoelectrodes in milliseconds

J Zhang, Y Zou, S Eickelmann, C Njel, T Heil… - Nature …, 2021‏ - nature.com
Fabrication of hybrid photoelectrodes on a subsecond timescale with low energy
consumption and possessing high photocurrent densities remains a centerpiece for …

Integrating high mannose-binding aptamer and CRISPR/Cas12a machinery for the remote detection of cell surface high mannose

S Liu, X Bian, F Zhao, M Cao, Z Shang, B Li… - Sensors and Actuators B …, 2024‏ - Elsevier
High mannose is overexpressed on the cell surface during carcinogenesis; however, there
are currently no efficient techniques for its detection. Herein, we propose an assay called …