As crucial antigen presenting cells, dendritic cells (DCs) play a vital role in tumor
immunotherapy. Taking into account the many recent advances in DC biology, we discuss …

C-type lectin receptors (CLRs) expressed by myeloid cells constitute a versatile family of
receptors that play a key role in innate immune recognition. Myeloid CLRs exhibit a …

The occurrence of the novel severe acute respiratory syndrome coronavirus-2 (SARS-CoV-
2), responsible for coronavirus disease 2019 (COVD-19), represents a catastrophic threat to …

Tuberculosis (TB) remains a significant global health challenge, claiming the lives of up to
1.5 million individuals annually. TB is caused by the human pathogen Mycobacterium …

Objective: To conduct a meta-analysis of current studies that examined sex differences in
severity and mortality in patients with COVID-19, and identify potential mechanisms …

Neuroinflammation exacerbates the progression of SOD1-driven amyotrophic lateral
sclerosis (ALS), although the underlying mechanisms remain largely unknown. Herein, we …

The influenza A virus (IAV) envelope protein hemagglutinin binds α2, 6-or α2, 3-linked sialic
acid as a host cell receptor. Bat IAV subtypes H17N10 and H18N11 form an exception to this …

Smokers with apparently “healthy” lungs suffer from more severe and frequent viral
respiratory infections, but the mechanisms underlying this observation are still unclear …

Programmed cell death is a critical host defence strategy during viral infection. Neighbouring
cells deal with this death in distinct ways depending on how the infected cell dies. While …

The use of soluble fusion proteins of pattern recognition receptors (PRRs) used in the
detection of exogenous and endogenous ligands has helped resolve the roles of PRRs in …