Functions of hydrotropes in solutions

CV Subbarao, IPK Chakravarthy… - Chemical …, 2012‏ - Wiley Online Library
Hydrotropes affect a several‐fold increase of the solubility of sparingly soluble solutes under
normal conditions. Their water‐solubility can significantly enhance the solubility of organic …

[HTML][HTML] Hydrotropy and Co-Solvency: Sustainable Strategies for Enhancing Solubility of Poorly Soluble Pharmaceutical Active Ingredients

MA El Hamd, RH Obaydo, D Nashed, M El-Maghrabey… - Talanta Open, 2024‏ - Elsevier
This review explores sustainable strategies for enhancing the solubility of poorly water-
soluble pharmaceutical active ingredients (PAIs), focusing on hydrotropy and co-solvency …

[HTML][HTML] Novel UV spectrophotometer methods for quantitative estimation of metronidazole and furazolidone using mixed hydrotropy solubilization

R Jain, N Jain, DK Jain, VK Patel, H Rajak… - Arabian Journal of …, 2017‏ - Elsevier
Two simple, accurate, novel, safe and precise methods were developed for the
simultaneous estimation of poorly water-soluble drugs Metronidazole (MTR) and …

Hydrotropic solubilization in pharmaceutical analysis: Origin, evolution, cumulative trend and precise applications

MR Patil, SB Ganorkar, AS Patil… - Critical reviews in …, 2021‏ - Taylor & Francis
The hydrotropy though existing as precisely used scientific approach assisting solubilization
for all. It took 66 long years to use the concept in drug analysis since its inception in 1916 …

[PDF][PDF] Solubility enhancement methods with importance of hydrotropy

MA Sajid, V Choudhary - Journal of Drug Delivery & Therapeutics, 2012‏ - core.ac.uk
The effectiveness of formulation depends particularly on how efficiently is drug available at
the site of action. Therapeutic effectiveness of a drug basically depends upon bioavailability …

[PDF][PDF] Novel UV Spectrophotometer Methods for Quantitative Estimation of Concensi (Amlodipine 10mg and Celecoxib 200mg) Using Hydrotropic Solubilizing Agents.

D Kushwaha, S Diwakar, RK Roy, S Karole… - Journal of Drug …, 2019‏ - core.ac.uk
Two simple, accurate, novel, safe and precise methods were developed for the
simultaneous estimation of poorly water-soluble drugs Amlodipine besylate (AMD) and …

A novel approach using hydrotropic solubalization technique for quantitative estimation of entacapone in bulk drug and dosage form

R Jain, N Jain, DK Jain, SK Jain - Advanced pharmaceutical …, 2013‏ - pmc.ncbi.nlm.nih.gov
Purpose: Analysis of drug utilized the organic solvent which are costlier, toxic and causing
environment pollution. Hydrotropic solution may be a proper choice to preclude the use of …

[PDF][PDF] Potentiometric membrane sensors for determination of memantine hydrochloride and pramipexole dihydrochloride monohydrate

HA Merey, MI Helmy, SM Tawakkol… - Portugaliae …, 2012‏ - academia.edu
Five solid membrane sensors responsive to memantine hydrochloride (MEM) and
pramipexole dihydrochloride monohydrate (PXL) are described for simple and fast …

Eco friendly spectrophotometric method for quantitative estimation of lomefloxacin using hydrotropic approach

R Jain, V Jain, N Jain, DK Jain, S Jain - Journal of Applied …, 2012‏ - japsonline.com
The present work describes a novel, accurate, sensitive and economic safe
spectrophotometric method was developed by application of hydrotropy, using 8 M Urea …

Green hydrotropic technology as a convenient tool for the handling of poor water-soluble candidates proceeding their economic analytical measurements

MA El Hamd, MH El-Maghrabey, S Almawash… - … Chemical Analysis and …, 2022‏ - Springer
An acceptable, safe, and green technique for solubilization of poorly soluble drugs is the
major important initial step for their handling through analytical work. Various procedures …