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Perspectives on the integration between first-principles and data-driven modeling
Efficiently embedding and/or integrating mechanistic information with data-driven models is
essential if it is desired to simultaneously take advantage of both engineering principles and …
essential if it is desired to simultaneously take advantage of both engineering principles and …
Towards smart biomanufacturing: a perspective on recent developments in industrial measurement and monitoring technologies for bio-based production processes
The biomanufacturing industry has now the opportunity to upgrade its production processes
to be in harmony with the latest industrial revolution. Technology creates capabilities that …
to be in harmony with the latest industrial revolution. Technology creates capabilities that …
Scrutinizing environmental governance in a digital age: New ways of seeing, participating, and intervening
Digital technologies play an increasingly important role in addressing environmental
challenges, such as climate change and resource depletion. Yet, the characteristics and …
challenges, such as climate change and resource depletion. Yet, the characteristics and …
[HTML][HTML] Machine learning for industrial sensing and control: A survey and practical perspective
With the rise of deep learning, there has been renewed interest within the process industries
to utilize data on large-scale nonlinear sensing and control problems. We identify key …
to utilize data on large-scale nonlinear sensing and control problems. We identify key …
Hybrid modeling in bioprocess dynamics: Structural variabilities, implementation strategies, and practical challenges
Hybrid modeling, with an appropriate blend of the mechanistic and data‐driven framework,
is increasingly being adopted in bioprocess modeling, model‐based experimental design …
is increasingly being adopted in bioprocess modeling, model‐based experimental design …
Digital Twin in biomanufacturing: Challenges and opportunities towards its implementation
The domain of industrial biomanufacturing is enthusiastically embracing the concept of
Digital Twin, owing to its promises of increased process efficiency and resource utilisation …
Digital Twin, owing to its promises of increased process efficiency and resource utilisation …
Steering representations—towards a critical understanding of digital twins
Digital Twins are conceptualised in the academic technical discourse as real-time realistic
digital representations of physical entities. Originating from product engineering, the Digital …
digital representations of physical entities. Originating from product engineering, the Digital …
Towards the development of digital twins for the bio-manufacturing industry
The bio-manufacturing industry, along with other process industries, now has the opportunity
to be engaged in the latest industrial revolution, also known as Industry 4.0. To successfully …
to be engaged in the latest industrial revolution, also known as Industry 4.0. To successfully …
[HTML][HTML] Why is batch processing still dominating the biologics landscape? Towards an integrated continuous bioprocessing alternative
Continuous manufacturing of biologics (biopharmaceuticals) has been an area of active
research and development for many reasons, ranging from the demand for operational …
research and development for many reasons, ranging from the demand for operational …
The role of big data in industrial (bio) chemical process operations
With the emergence of Industry 4.0 and Big Data initiatives, there is a renewed interest in
leveraging the vast amounts of data collected in (bio) chemical processes to improve their …
leveraging the vast amounts of data collected in (bio) chemical processes to improve their …