[HTML][HTML] Therapeutic potential of natural products in treating neurodegenerative disorders and their future prospects and challenges

MH Rahman, J Bajgai, A Fadriquela, S Sharma… - Molecules, 2021 - mdpi.com
Natural products derived from plants, as well as their bioactive compounds, have been
extensively studied in recent years for their therapeutic potential in a variety of …

Natural products and their bioactive compounds: neuroprotective potentials against neurodegenerative diseases

NS Mohd Sairazi… - … Based Complementary and …, 2020 - Wiley Online Library
In recent years, natural products, which originate from plants, animals, and fungi, together
with their bioactive compounds have been intensively explored and studied for their …

Oxidative stress in Parkinson's disease: Potential benefits of antioxidant supplementation

S Percário, A da Silva Barbosa… - Oxidative medicine …, 2020 - Wiley Online Library
Parkinson's disease (PD) occurs in approximately 1% of the population over 65 years of age
and has become increasingly more common with advances in age. The number of …

Multifaceted role of polyphenols in the treatment and management of neurodegenerative diseases

F Islam, MM Islam, AFK Meem, MH Nafady, MR Islam… - Chemosphere, 2022 - Elsevier
Neurodegenerative diseases (NDDs) are conditions that cause neuron structure and/or
function to deteriorate over time. Genetic alterations may be responsible for several NDDs …

[HTML][HTML] Dietary antioxidants and Parkinson's disease

HA Park, AC Ellis - Antioxidants, 2020 - mdpi.com
Parkinson's disease (PD) is a neurodegenerative disorder caused by the depletion of
dopaminergic neurons in the basal ganglia, the movement center of the brain …

[HTML][HTML] An oleuropein rich-olive (Olea europaea L.) leaf extract reduces β-amyloid and tau proteotoxicity through regulation of oxidative-and heat shock-stress …

JM Romero-Márquez, MD Navarro-Hortal… - Food and Chemical …, 2022 - Elsevier
Olive tree-derived products have been associated with numerous benefits for health. The
aim of the present study was to characterize an olive leaf extract enriched in oleuropein …

Molecular mechanisms of the protective effects of olive leaf polyphenols against Alzheimer's disease

JM Romero-Márquez, TY Forbes-Hernández… - International Journal of …, 2023 - mdpi.com
Alzheimer's Disease (AD) is the cause of around 60–70% of global cases of dementia and
approximately 50 million people have been reported to suffer this disease worldwide. The …

Neuroprotective effects of oleuropein: Recent developments and contemporary research

MS Butt, U Tariq, A Naz… - Journal of Food …, 2021 - Wiley Online Library
Neurological disorders are increasing at a faster pace due to oxidative stress, protein
aggregation, excitotoxicity, and neuroinflammation. It is reported that the Mediterranean diet …

Potential role of natural polyphenols against protein aggregation toxicity: in vitro, in vivo, and clinical studies

G Henríquez, A Gomez, E Guerrero… - ACS Chemical …, 2020 - ACS Publications
One of the main features of neurodegenerative disorders such as Alzheimer's disease and
Parkinson's disease is the amyloidogenic behavior of disease-specific proteins including …

Olive leaf extract (OLE) as a novel antioxidant that ameliorates the inflammatory response in cystic fibrosis

C Allegretta, G Difonzo, F Caponio, G Tamma… - Cells, 2023 - mdpi.com
The deletion of phenylalanine at position 508 (F508del) produces a misfolded CFTR protein
that is retained in the ER and degraded. The lack of normal CFTR channel activity is …