Research on the discovery and characterization of small, regulatory RNAs in bacteria has
exploded in recent years. These sRNAs act by base pairing with target mRNAs with which …

It is now well established that small RNAs (sRNAs) have diverse and widespread roles in
regulating gene expression in all organisms (1–4). Mechanisms of action are varied but can …

6S RNA is a small, noncoding RNA that interacts with the primary holoenzyme form of RNA
polymerase. Escherichia coli 6S RNA is a global regulator that downregulates transcription …

Rho factor is a molecular motor that translocates along nascent RNA and acts on the
transcription elongation complex to promote termination. Besides contributing to …

Abstract 6S RNAs function through interaction with housekee** forms of RNA polymerase
holoenzyme (Eσ70 in Escherichia coli, EσA in Bacillus subtilis). Escherichia coli 6S RNA …

Abstract Background Small non-coding RNAs (sRNA) are emerging as major components of
the cell's regulatory network, several possessing their own regulons. A few sRNAs have …

Ms1 is a sRNA recently found in mycobacteria and several other actinobacterial species.
Ms1 interacts with the RNA polymerase (RNAP) core devoid of sigma factors, which differs …

Whereas, the majority of bacterial non-coding RNAs and functional RNA elements regulate
post-transcriptional processes, either by interacting with other RNAs via base-pairing or …

Bacterial small RNAs (sRNAs) are important post-transcriptional regulators in stress
responses and virulence. They can be derived from an expanding list of genomic contexts …

Mycobacterium tuberculosis (Mtb), the etiologic agent of tuberculosis, must adapt to host‐
associated environments during infection by modulating gene expression. Small regulatory …