From chemotherapy to biological therapy: A review of novel concepts to reduce the side effects of systemic cancer treatment

V Schirrmacher - International journal of oncology, 2019 - spandidos-publications.com
The side effects of systemic chemotherapy used to treat cancer are often severe. For
decades, oncologists have focused on treating the tumor, which may result in damage to the …

Inflammatory bowel disease and cancer: The role of inflammation, immunosuppression, and cancer treatment

JE Axelrad, S Lichtiger, V Yajnik - World journal of …, 2016 - pmc.ncbi.nlm.nih.gov
In patients with inflammatory bowel disease (IBD), chronic inflammation is a major risk factor
for the development of gastrointestinal malignancies. The pathogenesis of colitis-associated …

Cancers complicating inflammatory bowel disease

L Beaugerie, SH Itzkowitz - New England Journal of Medicine, 2015 - Mass Medical Soc
Cancers Complicating Inflammatory Bowel Disease | New England Journal of Medicine Skip to
main content The New England Journal of Medicine homepage Advanced Search SEARCH …

European evidence-based consensus: inflammatory bowel disease and malignancies

V Annese, L Beaugerie, L Egan… - Journal of Crohn's …, 2015 - academic.oup.com
The global prevalence of cancer is increasing, largely as more patients are living into old
age. Therefore, gastroenterologists caring for patients with inflammatory bowel disease [IBD] …

Bacterial pigments and their multifaceted roles in contemporary biotechnology and pharmacological applications

H Agarwal, S Bajpai, A Mishra, I Kohli, A Varma… - Microorganisms, 2023 - mdpi.com
Synthetic dyes and colourants have been the mainstay of the pigment industry for decades.
Researchers are eager to find a more environment friendly and non-toxic substitute because …

Rapamycin and mTOR kinase inhibitors

LM Ballou, RZ Lin - Journal of chemical biology, 2008 - Springer
Mammalian target of rapamycin (mTOR) is a protein kinase that controls cell growth,
proliferation, and survival. mTOR signaling is often upregulated in cancer and there is great …

Emerging treatment approaches for Parkinson's disease

TB Stoker, KM Torsney, RA Barker - Frontiers in neuroscience, 2018 - frontiersin.org
Parkinson's disease (PD) is the second most common neurodegenerative disease,
manifesting as a characteristic movement disorder with a number of additional non-motor …

Indoleamine 2, 3‐dioxygenase in T‐cell tolerance and tumoral immune escape

JB Katz, AJ Muller, GC Prendergast - Immunological reviews, 2008 - Wiley Online Library
Indoleamine 2, 3‐dioxygenase (IDO) degrades the essential amino acid tryptophan in
mammals, catalyzing the initial and rate‐limiting step in the de novo biosynthesis …

Human regulatory T cells: understanding the role of tregs in select autoimmune skin diseases and post-transplant nonmelanoma skin cancers

NC Oparaugo, K Ouyang, NPN Nguyen… - International journal of …, 2023 - mdpi.com
Regulatory T cells (Tregs) play an important role in maintaining immune tolerance and
homeostasis by modulating how the immune system is activated. Several studies have …

Utilizing Sertoli Cell Transplantation as a Therapeutic Technique for the Management of Neurodegenerative Diseases

H Ahmady, M Afrand, M Motaqi… - Archives of Razi …, 2024 - archrazi.areeo.ac.ir
Neurodegenerative diseases (NDs) such as, Alzheimer's disease (AD), Parkinson's disease
(PD), amyotrophic lateral sclerosis (ALS), and Huntington's disease (HD), are defined by …