Nanomaterial-synergized photodynamic therapy (PDT) and photothermal therapy (PTT), as
efficient and non-invasive treatment modalities, have shown significant advantages in …

Hypoxia, a salient feature of most solid tumors, confers invasiveness and resistance to the
tumor cells. Oxygen-consumption photodynamic therapy (PDT) suffers from the undesirable …

The anti-tumor activity of the immune system is increasingly recognized as critical for the
mounting of a prolonged and effective response to cancer growth and invasion, and for …

In cancer imaging, nanoparticle biodistribution is typically visualized in living subjects using
'bulk'imaging modalities such as magnetic resonance imaging, computerized tomography …

Nanoparticles promise to improve the treatment of cancer through their increasingly
sophisticated functionalisations and ability to accumulate in certain tumours. Yet recent work …

Despite a growing wealth of available molecular data, the growth of tumors, invasion of
tumors into healthy tissue, and response of tumors to therapies are still poorly understood …

Drug resistance significantly limits the long-term effectiveness of targeted therapeutics for
cancer patients. Recent experimental studies have demonstrated that cancer cell …

Introduction: A defining hallmark of cancer is aberrant cell proliferation. Efforts to understand
the generative properties of cancer cells span all biological scales: from genetic deviations …

Background Multidrug resistance (MDR) is one of the major reasons chemotherapy-based
treatments fail. Hypoxia is generally associated with tumor chemoresistance. However, the …

Hypoxia is a characteristic feature of solid tumors and an important causation of resistance
to chemotherapy and photodynamic therapy (PDT). It is challenging to develop efficient …