Gammaherpesviruses are an important class of oncogenic pathogens that are exquisitely
evolved to their respective hosts. As such, the human gammaherpesviruses Epstein-Barr …

Many viruses induce shutoff of host gene expression (host shutoff) as a strategy to take over
cellular machinery and evade host immunity. Without host shutoff activity, these viruses …

Kaposi's sarcoma herpesvirus (KSHV) is an oncogenic human virus and the leading cause
of mortality in HIV infection. KSHV reactivation from latent-to lytic-stage infection initiates a …

How human cytomegalovirus (HCMV) infection impacts the transcription of the host genome
remains incompletely understood. Here, we examine the global consequences of infection …

The battle for control of gene expression is central to the outcome of a virus–host interaction.
On the cellular side, mounting an effective innate immune response to infection requires …

RNA abundance is generally sensitive to perturbations in decay and synthesis rates, but
crosstalk between RNA polymerase II transcription and cytoplasmic mRNA degradation …

Feline calicivirus (FCV) belongs to the Caliciviridae, which comprises small RNA viruses of
both medical and veterinary importance. Once infection has occurred, FCV can persist in the …

Control of gene expression, including transcription, is central in dictating the outcome of viral
infection. One of the profound alterations induced by viruses is modification to the integrity …

β-and γ-herpesviruses include the oncogenic human viruses Kaposi's sarcoma-associated
virus (KSHV) and Epstein-Barr virus (EBV), and human cytomegalovirus (HCMV), which is a …

Viral infections and the harm they cause to their host are a perpetual threat to living
organisms. Pathogenesis and subsequent spread of infection requires replication of the viral …