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Exosome processing and characterization approaches for research and technology development
Exosomes are extracellular vesicles that share components of their parent cells and are
attractive in biotechnology and biomedical research as potential disease biomarkers as well …
attractive in biotechnology and biomedical research as potential disease biomarkers as well …
Application of exosomes as liquid biopsy in clinical diagnosis
B Zhou, K Xu, X Zheng, T Chen, J Wang… - Signal transduction and …, 2020 - nature.com
Liquid biopsy refers to the sampling and molecular analysis of the biofluids of circulating
tumor cells, extracellular vesicles, nucleic acids, and so forth. Exosomes are small …
tumor cells, extracellular vesicles, nucleic acids, and so forth. Exosomes are small …
Extracellular miRNAs: from biomarkers to mediators of physiology and disease
MA Mori, RG Ludwig, R Garcia-Martin, BB Brandão… - Cell metabolism, 2019 - cell.com
miRNAs can be found in serum and other body fluids and serve as biomarkers for disease.
More importantly, secreted miRNAs, especially those in extracellular vesicles (EVs) such as …
More importantly, secreted miRNAs, especially those in extracellular vesicles (EVs) such as …
miRNAS in cardiovascular diseases: potential biomarkers, therapeutic targets and challenges
S Zhou, J **, J Wang, Z Zhang, JH Freedman… - Acta Pharmacologica …, 2018 - nature.com
Cardiovascular diseases (CVD) are the leading cause of morbidity and mortality in the
world. Although considerable progress has been made in the diagnosis, treatment and …
world. Although considerable progress has been made in the diagnosis, treatment and …
Extracellular vesicles in cardiovascular disease: Biological functions and therapeutic implications
Extracellular vesicles (EVs), including exosomes and microvesicles, are lipid bilayer
particles naturally released from the cell. While exosomes are formed as intraluminal …
particles naturally released from the cell. While exosomes are formed as intraluminal …
[HTML][HTML] Methodologies to isolate and purify clinical grade extracellular vesicles for medical applications
The use of extracellular vesicles (EV) in nano drug delivery has been demonstrated in many
previous studies. In this study, we discuss the sources of extracellular vesicles, including …
previous studies. In this study, we discuss the sources of extracellular vesicles, including …
Circulating noncoding RNAs as biomarkers of cardiovascular disease and injury
J Viereck, T Thum - Circulation research, 2017 - ahajournals.org
The discovery of thousands of noncoding RNAs (ncRNAs) has expanded our view on
mammalian genomes and transcriptomes, as well as their organization and regulation …
mammalian genomes and transcriptomes, as well as their organization and regulation …
Extracellular vesicles in diagnostics and therapy of the ischaemic heart: Position Paper from the Working Group on Cellular Biology of the Heart of the European …
Extracellular vesicles (EVs)—particularly exosomes and microvesicles (MVs)—are attracting
considerable interest in the cardiovascular field as the wide range of their functions is …
considerable interest in the cardiovascular field as the wide range of their functions is …
Cell cycle regulation of stem cells by microRNAs
MMJ Mens, M Ghanbari - Stem cell reviews and reports, 2018 - Springer
MicroRNAs (miRNAs) are a class of small non-coding RNA molecules involved in the
regulation of gene expression. They are involved in the fine-tuning of fundamental biological …
regulation of gene expression. They are involved in the fine-tuning of fundamental biological …
MicroRNA and cardiovascular diseases
HA Çakmak, M Demir - Balkan medical journal, 2020 - pmc.ncbi.nlm.nih.gov
Cardiovascular diseases are one of the most common causes of death in both develo**
and developed countries worldwide. Even though there have been improvements in primary …
and developed countries worldwide. Even though there have been improvements in primary …