Plant viral diseases are major constraints causing significant yield losses worldwide in
agricultural and horticultural crops. The commonly used methods cannot eliminate viral load …

Although translational selection to favour codons that match the most abundant tRNAs is not
readily observed in humans, there is nonetheless selection in humans on synonymous …

The secretory enzyme human ribonuclease 1 (RNase1) is involved in innate immunity and
anti-inflammation, achieving host defense and anti-cancer effects; however, whether …

Pancreatic-type ribonucleases (ptRNases) are a large family of vertebrate-specific secretory
endoribonucleases. These enzymes catalyze the degradation of many RNA substrates and …

Dengue virus (DENV) and Zika virus (ZIKV) capsid proteins efficiently recruit and surround
the viral RNA at the endoplasmic reticulum (ER) membrane to yield nascent viral particles …

The CD8+ T cell noncytotoxic antiviral response (CNAR) was discovered during studies of
asymptomatic HIV-infected subjects more than 30 years ago. In contrast to CD8+ T cell …

Recent developments in next-generation sequencing technologies have greatly facilitated
the study of whole transcriptomes in model and non-model species. Studying the …

Owing to the recent outbreak of Coronavirus Disease of 2019 (COVID-19), it is urgent to
develop effective and safe drugs to treat the present pandemic and prevent other viral …

The majority of transcribed RNAs do not codify for proteins, nevertheless they display crucial
regulatory functions by affecting the cellular protein expression profile. MicroRNAs (miRNAs) …

Bacillus pumilus ribonuclease (binase) was shown to be a promising antiviral agent in
animal models and cell cultures. However, the mode of its antiviral action remains unknown …