Pharmaceutical nanotechnology: Antimicrobial peptides as potential new drugs against WHO list of critical, high, and medium priority bacteria

CA Roque-Borda, PB Da Silva, MC Rodrigues… - European Journal of …, 2022 - Elsevier
Nanobiotechnology is a relatively unexplored area that has, nevertheless, shown relevant
results in the fight against some diseases. Antimicrobial peptides (AMPs) are …

Recent advances in research for potential utilization of unexplored lichen metabolites

R Kalra, XA Conlan, M Goel - Biotechnology Advances, 2023 - Elsevier
Several research studies have shown that lichens are productive organisms for the
synthesis of a broad range of secondary metabolites. Lichens are a self-sustainable stable …

Phage-antibiotic combinations in various treatment modalities to manage MRSA infections

A Loganathan, B Bozdogan, P Manohar… - Frontiers in …, 2024 - frontiersin.org
Introduction: The emergence of antibiotic resistance is a significant challenge in the
treatment of bacterial infections, particularly in patients in the intensive care unit (ICU) …

A new approach to overcoming antibiotic-resistant bacteria: traditional chinese medicine therapy based on the gut microbiota

P Xue, R Sang, N Li, S Du, X Kong, M Tai… - Frontiers in cellular …, 2023 - frontiersin.org
With the irrational use of antibiotics and the increasing abuse of oral antibiotics, the drug
resistance of gastrointestinal pathogens has become a prominent problem in clinical …

A review on the diversity of antimicrobial peptides and genome mining strategies for their prediction

N Kumar, P Bhagwat, S Singh, S Pillai - Biochimie, 2024 - Elsevier
Antibiotic resistance has become one of the most serious threats to human health in recent
years. In response to the increasing microbial resistance to the antibiotics currently …

[HTML][HTML] The natural compound hydrophobic usnic acid and hydrophilic potassium usnate derivative: Applications and comparisons

HDA Araújo, HAMF Silva, JG Silva Júnior… - Molecules, 2021 - mdpi.com
Usnic acid is the best-studied lichen metabolite, presenting several biological activities, such
as antibacterial, immunostimulating, antiviral, antifungal, anti-inflammatory, and antiparasitic …

Discovery of novel Staphylococcus aureus penicillin binding protein 2a inhibitors by multistep virtual screening and biological evaluation

N Lv, Q Kong, H Zhang, J Li - Bioorganic & Medicinal Chemistry Letters, 2021 - Elsevier
Penicillin-binding protein 2a (PBP2a) is an essential protein involved in the resistance to β-
lactam antibiotics acquired by methicillin-resistant Staphylococcus aureus (MRSA) and is a …

Repurposing Amphotericin B: anti-microbial, molecular docking and molecular dynamics simulation studies suggest inhibition potential of Amphotericin B against …

N Farid, K Bux, K Ali, A Bashir, R Tahir - BMC chemistry, 2023 - Springer
Amphotericin B (AMPH) is an anti-fungal drug and this study, for the first time as best of our
knowledge, reports the repurposing of the Amphotericin B. The drug was found to show …

Anti-yeast potential of lichen-extracted substances–an analytical review

Ł Furmanek, MRD Seaward - South African Journal of Botany, 2023 - Elsevier
A meta-analysis of literature data with statistical analysis concerning the effect of lichen
substances on the inhibition of 10 yeast species (Candida albicans, C. dubliniensis, C …

[HTML][HTML] Antibacterial Activity and Mechanism of Canagliflozin against Methicillin-Resistant Staphylococcus aureus

S Gu, B Fan, F Wan, T Gao, Y Qi, J Zhou, Y Zhang… - Molecules, 2023 - mdpi.com
Diabetic foot infection (DFI) is a common complication in diabetes patients, with foot
infections being the leading cause of amputations. Staphylococcus aureus is frequently …