Metabolic rewiring and epigenetic remodeling, which are closely linked and reciprocally
regulate each other, are among the well-known cancer hallmarks. Recent evidence …

Histone posttranslational modifications are key components of diverse processes that
modulate chromatin structure. These marks function as signals during various chromatin …

Chronic obstructive pulmonary disease (COPD) is a major incurable global health burden
and is currently the 4th largest cause of death in the world. Importantly, much of the disease …

Arsenic is a notorious element with the potential to harm exposed individuals in ways that
include cancerous and non-cancerous health complications. Millions of people across the …

Oncogenesis is a multistep process mediated by a variety of factors including epigenetic
modifications. Global epigenetic post-translational modifications have been detected in …

Epstein-Barr virus (EBV) infection is associated with a variety of malignancies including
Burkitt's lymphoma (BL), Hodgkin's disease, T cell lymphoma, nasopharyngeal carcinoma …

Exposure to toxic metals poses a serious human health hazard based on ubiquitous
environmental presence, the extent of exposure, and the toxicity and disease states …

Purpose: Cancer-initiating cells (CIC) are considered to represent the subpopulation of
tumor cells that is resistant to conventional cancer treatments, highly tumorigenic in …

Purpose: Genetic analysis of bladder cancer has revealed a number of frequently altered
genes, including frequent alterations of the telomerase (TERT) gene promoter, although few …

Cancer, once thought to be caused largely by genetic alterations, is now considered to be a
mixed genetic and epigenetic disease. The epigenetic landscape, which is dictated by …