[HTML][HTML] Progress in develo** inhibitors of SARS-CoV-2 3C-like protease

Q Li, CB Kang - Microorganisms, 2020 - mdpi.com
Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2). The viral outbreak started in late 2019 and rapidly became a …

Revisiting pharmacological potentials of Nigella sativa seed: A promising option for COVID‐19 prevention and cure

MN Islam, KS Hossain, PP Sarker… - Phytotherapy …, 2021 - Wiley Online Library
Nigella sativa seed and its active compounds have been historically recognized as an
effective herbal panacea that can establish a balanced inflammatory response by …

Hamster models of COVID-19 pneumonia reviewed: How human can they be?

AD Gruber, TC Firsching, J Trimpert… - Veterinary …, 2022 - journals.sagepub.com
The dramatic global consequences of the coronavirus disease 2019 (COVID-19) pandemic
soon fueled quests for a suitable model that would facilitate the development and testing of …

Prospects of honey in fighting against COVID-19: pharmacological insights and therapeutic promises

KS Hossain, MG Hossain, A Moni, MM Rahman… - Heliyon, 2020 - cell.com
Honey and its compounds are drawing attention as an effective natural therapy because of
its ability to attenuate acute inflammation through enhancing immune response. Several …

COVID-19: pathogenesis, advances in treatment and vaccine development and environmental impact—an updated review

YA Attia, MT El-Saadony, AA Swelum… - … Science and Pollution …, 2021 - Springer
Diseases negatively impact the environment, causing many health risks and the spread of
pollution and hazards. A novel coronavirus, severe acute respiratory syndrome coronavirus …

[HTML][HTML] Assessing the potential contribution of in silico studies in discovering drug candidates that interact with various SARS-CoV-2 receptors

AGA Mushebenge, SC Ugbaja, NA Mbatha… - International Journal of …, 2023 - mdpi.com
The COVID-19 pandemic has spurred intense research efforts to identify effective treatments
for SARS-CoV-2. In silico studies have emerged as a powerful tool in the drug discovery …

Intestinal organoids: A versatile platform for modeling gastrointestinal diseases and monitoring epigenetic alterations

M Ghorbaninejad, H Asadzadeh-Aghdaei… - Life Sciences, 2023 - Elsevier
Considering the significant limitations of conventional 2D cell cultures and tissue in vitro
models, creating intestinal organoids has burgeoned as an ideal option to recapitulate the …

Structural, dynamic behaviour, in-vitro and computational investigations of Schiff's bases of 1, 3-diphenyl urea derivatives against SARS-CoV-2 spike protein

S Ullah, A Ullah, M Waqas, SA Halim, AR Pasha… - Scientific Reports, 2024 - nature.com
The COVID-19 has had a significant influence on people's lives across the world. The viral
genome has undergone numerous unanticipated changes that have given rise to new …

Role and clinical implication of autophagy in COVID-19

T Shan, L Li, JM Yang, Y Cheng - Virology Journal, 2023 - Springer
The ongoing coronavirus disease 2019 (COVID-19) pandemic constitutes a serious public
health concern worldwide. Currently, more than 6 million deaths have occurred despite …

Papaverine, a promising therapeutic agent for the treatment of COVID‐19 patients with underlying cardiovascular diseases (CVDs)

M Valipour, H Irannejad… - Drug development …, 2022 - Wiley Online Library
The causative agent of coronavirus disease‐2019 (COVID‐19), severe acute respiratory
syndrome coronavirus 2 (SARS‐CoV‐2), enters the host cells via an angiotensin‐converting …