Bioactive sphingolipids as emerging targets for signal transduction in cancer development
W Jia, J Yuan, J Zhang, S Li, W Lin, B Cheng - Biochimica et Biophysica …, 2024 - Elsevier
Sphingolipids, crucial components of cellular membranes, play a vital role in maintaining
cellular structure and signaling integrity. Disruptions in sphingolipid metabolism are …
cellular structure and signaling integrity. Disruptions in sphingolipid metabolism are …
Continuum models of membrane fusion: Evolution of the theory
SA Akimov, RJ Molotkovsky, PI Kuzmin… - International journal of …, 2020 - mdpi.com
Starting from fertilization, through tissue growth, hormone secretion, synaptic transmission,
and sometimes morbid events of carcinogenesis and viral infections, membrane fusion …
and sometimes morbid events of carcinogenesis and viral infections, membrane fusion …
Are There Lipid Membrane-Domain Subtypes in Neurons with Different Roles in Calcium Signaling?
AK Samhan-Arias, J Poejo, D Marques-da-Silva… - Molecules, 2023 - mdpi.com
Lipid membrane nanodomains or lipid rafts are 10–200 nm diameter size cholesterol-and
sphingolipid-enriched domains of the plasma membrane, gathering many proteins with …
sphingolipid-enriched domains of the plasma membrane, gathering many proteins with …
Elastic deformations mediate interaction of the raft boundary with membrane inclusions leading to their effective lateral sorting
Liquid-ordered lipid domains represent a lateral inhomogeneity in cellular membranes.
These domains have elastic and physicochemical properties different from those of the …
These domains have elastic and physicochemical properties different from those of the …
Toxic effects of penetrating cations
As mitochondria are negatively charged organelles, penetrating cations are used as parts of
chimeric molecules to deliver specific compounds into mitochondria. In other words, they are …
chimeric molecules to deliver specific compounds into mitochondria. In other words, they are …
Organization of gangliosides into membrane nanodomains
Gangliosides are glycosphingolipids consisting of a ceramide base and a bulky sugar chain
that contains one or more sialic acids. This unique structure endows gangliosides with a …
that contains one or more sialic acids. This unique structure endows gangliosides with a …
Ordered lipid domains assemble via concerted recruitment of constituents from both membrane leaflets
Lipid rafts serve as anchoring platforms for membrane proteins. Thus far they escaped direct
observation by light microscopy due to their small size. Here we used differently colored …
observation by light microscopy due to their small size. Here we used differently colored …
Membrane-mediated interaction of amphipathic peptides can be described by a one-dimensional approach
Amphipathic alpha-helical peptides, among other peripheral components of plasma
membranes, are promising antimicrobial agents. Partial incorporation of a peptide into a …
membranes, are promising antimicrobial agents. Partial incorporation of a peptide into a …
The cytoplasmic tail of influenza A virus hemagglutinin and membrane lipid composition change the mode of M1 protein association with the lipid bilayer
LV Kordyukova, PV Konarev, NV Fedorova… - Membranes, 2021 - mdpi.com
Influenza A virus envelope contains lipid molecules of the host cell and three integral viral
proteins: major hemagglutinin, neuraminidase, and minor M2 protein. Membrane-associated …
proteins: major hemagglutinin, neuraminidase, and minor M2 protein. Membrane-associated …
Amphipathic peptides impede lipid domain fusion in phase-separated membranes
Cell membranes are heterogeneous in lipid composition which leads to the phase
separation with the formation of nanoscopic liquid-ordered domains, also called rafts. There …
separation with the formation of nanoscopic liquid-ordered domains, also called rafts. There …