[HTML][HTML] Artificial intelligence in pharmaceutical sciences

M Lu, J Yin, Q Zhu, G Lin, M Mou, F Liu, Z Pan, N You… - Engineering, 2023 - Elsevier
Drug discovery and development affects various aspects of human health and dramatically
impacts the pharmaceutical market. However, investments in a new drug often go …

Application of machine learning in spatial proteomics

M Mou, Z Pan, M Lu, H Sun, Y Wang… - Journal of Chemical …, 2022 - ACS Publications
Spatial proteomics is an interdisciplinary field that investigates the localization and dynamics
of proteins, and it has gained extensive attention in recent years, especially the subcellular …

DrugMAP: molecular atlas and pharma-information of all drugs

F Li, J Yin, M Lu, M Mou, Z Li, Z Zeng, Y Tan… - Nucleic acids …, 2023 - academic.oup.com
The efficacy and safety of drugs are widely known to be determined by their interactions with
multiple molecules of pharmacological importance, and it is therefore essential to …

A transformer-based ensemble framework for the prediction of protein–protein interaction sites

M Mou, Z Pan, Z Zhou, L Zheng, H Zhang, S Shi, F Li… - Research, 2023 - spj.science.org
The identification of protein–protein interaction (PPI) sites is essential in the research of
protein function and the discovery of new drugs. So far, a variety of computational tools …

Re-envisioning the design of nanomedicines: harnessing automation and artificial intelligence

J Zaslavsky, P Bannigan, C Allen - Expert Opinion on Drug …, 2023 - Taylor & Francis
Introduction Interest in nanomedicines has surged in recent years due to the critical role they
have played in the COVID-19 pandemic. Nanoformulations can turn promising therapeutic …

Computational insights into the cross-talk between medin and Aβ: implications for age-related vascular risk factors in Alzheimer's disease

F Huang, X Fan, Y Wang, Y Zou, J Lian… - Briefings in …, 2024 - academic.oup.com
The aggregation of medin forming aortic medial amyloid is linked to arterial wall
degeneration and cerebrovascular dysfunction. Elevated levels of arteriolar medin are …

Large Language Model-Based Natural Language Encoding Could Be All You Need for Drug Biomedical Association Prediction

H Zhang, Y Zhou, Z Zhang, H Sun, Z Pan… - Analytical …, 2024 - ACS Publications
Analyzing drug-related interactions in the field of biomedicine has been a critical aspect of
drug discovery and development. While various artificial intelligence (AI)-based tools have …

Identifying potential drug-target interactions based on ensemble deep learning

L Zhou, Y Wang, L Peng, Z Li, X Luo - Frontiers in Aging Neuroscience, 2023 - frontiersin.org
Introduction Drug-target interaction prediction is one important step in drug research and
development. Experimental methods are time consuming and laborious. Methods In this …

Advances in Artificial Intelligence in Drug Delivery and Development: A Comprehensive Review

AD Gholap, MJ Uddin, M Faiyazuddin, A Omri… - Computers in Biology …, 2024 - Elsevier
Artificial intelligence (AI) has emerged as a powerful tool to revolutionize the healthcare
sector, including drug delivery and development. This review explores the current and future …

Computational model for drug research

X Chen, L Huang - Briefings in Bioinformatics, 2024 - academic.oup.com
This special issue focuses on computational model for drug research regarding drug
bioactivity prediction, drug-related interaction prediction, modelling for immunotherapy and …