Mitochondria in innate immune responses
The innate immune system has a key role in the mammalian immune response. Recent
research has demonstrated that mitochondria participate in a broad range of innate immune …
research has demonstrated that mitochondria participate in a broad range of innate immune …
[HTML][HTML] Impact of COVID-19 on mitochondrial-based immunity in aging and age-related diseases
R Ganji, PH Reddy - Frontiers in Aging Neuroscience, 2021 - frontiersin.org
The coronavirus disease 2019 (COVID-19) is a deadly pandemic, immune compromised
disease with no cure. The COVID-19 is caused by acute respiratory syndrome corona virus 2 …
disease with no cure. The COVID-19 is caused by acute respiratory syndrome corona virus 2 …
SARS-CoV-2 ORF10 suppresses the antiviral innate immune response by degrading MAVS through mitophagy
X Li, P Hou, W Ma, X Wang, H Wang, Z Yu… - Cellular & molecular …, 2022 - nature.com
The global coronavirus disease 2019 (COVID-19) pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused severe morbidity and …
respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused severe morbidity and …
Mitochondrial interactome: a focus on antiviral signaling pathways
In the last years, proteomics has represented a valuable approach to elucidate key aspects
in the regulation of type I/III interferons (IFNs) and autophagy, two main processes involved …
in the regulation of type I/III interferons (IFNs) and autophagy, two main processes involved …
Influenza M2 protein regulates MAVS-mediated signaling pathway through interacting with MAVS and increasing ROS production
R Wang, Y Zhu, X Lin, C Ren, J Zhao, F Wang, X Gao… - Autophagy, 2019 - Taylor & Francis
Influenza A virus can evade host innate immune response that is involved in several viral
proteins with complicated mechanisms. To date, how influenza A M2 protein modulates the …
proteins with complicated mechanisms. To date, how influenza A M2 protein modulates the …
Mechanisms of MAVS regulation at the mitochondrial membrane
JL Jacobs, CB Coyne - Journal of molecular biology, 2013 - Elsevier
Mitochondria have emerged as critical platforms for antiviral innate immune signaling. This
is due in large part to the mitochondrial localization of the innate immune signaling adaptor …
is due in large part to the mitochondrial localization of the innate immune signaling adaptor …
COX5B regulates MAVS-mediated antiviral signaling through interaction with ATG5 and repressing ROS production
Y Zhao, X Sun, X Nie, L Sun, T Tang, D Chen… - PLoS …, 2012 - journals.plos.org
Innate antiviral immunity is the first line of the host defense system that rapidly detects
invading viruses. Mitochondria function as platforms for innate antiviral signal transduction in …
invading viruses. Mitochondria function as platforms for innate antiviral signal transduction in …
Regulation of RLR-mediated innate immune signaling–it is all about kee** the balance
K Eisenächer, A Krug - European journal of cell biology, 2012 - Elsevier
The current view of cytoplasmic RNA-mediated innate immune signaling involves the
differential activation of the RNA helicases retinoic acid-inducible gene 1 (RIG-I), melanoma …
differential activation of the RNA helicases retinoic acid-inducible gene 1 (RIG-I), melanoma …
[HTML][HTML] CFTR activity and mitochondrial function
Cystic Fibrosis (CF) is a frequent and lethal autosomal recessive disease, caused by
mutations in the gene encoding the Cystic Fibrosis Transmembrane Conductance Regulator …
mutations in the gene encoding the Cystic Fibrosis Transmembrane Conductance Regulator …
Zebrafish TMEM47 is an effective blocker of IFN production during RNA and DNA virus infection
LF Lu, ZC Li, C Zhang, DD Chen, KJ Han… - Journal of …, 2023 - Am Soc Microbiol
Mitochondrial antiviral signaling protein (MAVS) and stimulator of interferon (IFN) genes
(STING) are crucial factors of IFN induction in RNA and DNA viral infections. However …
(STING) are crucial factors of IFN induction in RNA and DNA viral infections. However …