The ovarian system comprises vital organs in females and is of great significance for the
maintenance of reproductive potential and endocrine stability. Although complex …

BACKGROUND Chemotherapy-associated ovarian damage (CAOD) is one of the most
feared short-and long-term side effects of anticancer treatment in premenopausal women …

Cisplatin is an important antineoplastic drug used in multiple chemotherapeutic regimens
but unfortunately causes serious toxic effects as ovarian and uterine toxicity. This study …

This study was designed to investigate the protective effect of resveratrol (RES) on
premature ovarian failure (POF) and the proliferation of female germline stem cells (FGSCs) …

The aims of the present study were to evaluate the protective effects of rutin during cisplatin-
induced ovarian toxicity in mice and to verify the possible involvement of the phosphatase …

Cisplatin (Cis) is an effective chemotherapeutic intervention against many cancer types.
However, the oxidative stress-related toxicities associated with cancer cell resistance …

Cancer is a significant disease burden worldwide. Chemotherapy is the mainstay of cancer
treatment. Clinically used chemotherapeutic agents may elicit severe side effects …

The incidence of common gynecological malignancies remains high, with current treatments
facing multiple limitations and adverse effects. Thus, continuing the search for safe and …

Cisplatin can lead to infertility due to its negative impact on the uterus and ovaries. This
study aimed to explore the effects of Inositol and vitamin C on cisplatin-induced infertility …

Background: The treatment of cancer is a current challenge for public health, causing high
rates of morbidity and mortality worldwide. Doxorubicin (DOX) and cisplatin (CP) are two …