Large-scale neural recordings call for new insights to link brain and behavior

AE Urai, B Doiron, AM Leifer, AK Churchland - Nature neuroscience, 2022 - nature.com
Neuroscientists today can measure activity from more neurons than ever before, and are
facing the challenge of connecting these brain-wide neural recordings to computation and …

Multiregion neuronal activity: the forest and the trees

TA Machado, IV Kauvar, K Deisseroth - Nature Reviews Neuroscience, 2022 - nature.com
The past decade has witnessed remarkable advances in the simultaneous measurement of
neuronal activity across many brain regions, enabling fundamentally new explorations of the …

Adult-born dentate granule cells promote hippocampal population sparsity

SB McHugh, V Lopes-dos-Santos, GP Gava… - Nature …, 2022 - nature.com
The dentate gyrus (DG) gates neocortical information flow to the hippocampus. Intriguingly,
the DG also produces adult-born dentate granule cells (abDGCs) throughout the lifespan …

Solving the spike sorting problem with Kilosort

M Pachitariu, S Sridhar, C Stringer - BioRxiv, 2023 - biorxiv.org
Spike sorting is the computational process of extracting the firing times of single neurons
from recordings of local electrical fields. This is an important but hard problem in …

Spike sorting with Kilosort4

M Pachitariu, S Sridhar, J Pennington, C Stringer - Nature Methods, 2024 - nature.com
Spike sorting is the computational process of extracting the firing times of single neurons
from recordings of local electrical fields. This is an important but hard problem in …

SpikeInterface, a unified framework for spike sorting

AP Buccino, CL Hurwitz, S Garcia, J Magland… - Elife, 2020 - elifesciences.org
Much development has been directed toward improving the performance and automation of
spike sorting. This continuous development, while essential, has contributed to an over …

[HTML][HTML] Neuronal computation underlying inferential reasoning in humans and mice

HC Barron, HM Reeve, RS Koolschijn, PV Perestenko… - Cell, 2020 - cell.com
Every day we make decisions critical for adaptation and survival. We repeat actions with
known consequences. But we also draw on loosely related events to infer and imagine the …

Removing independent noise in systems neuroscience data using DeepInterpolation

J Lecoq, M Oliver, JH Siegle, N Orlova… - Nature …, 2021 - nature.com
Progress in many scientific disciplines is hindered by the presence of independent noise.
Technologies for measuring neural activity (calcium imaging, extracellular electrophysiology …

[HTML][HTML] High-density single-unit human cortical recordings using the Neuropixels probe

JE Chung, KK Sellers, MK Leonard, L Gwilliams, D Xu… - Neuron, 2022 - cell.com
The action potential is a fundamental unit of neural computation. Even though significant
advances have been made in recording large numbers of individual neurons in animal …

Neural latents benchmark'21: evaluating latent variable models of neural population activity

F Pei, J Ye, D Zoltowski, A Wu, RH Chowdhury… - arxiv preprint arxiv …, 2021 - arxiv.org
Advances in neural recording present increasing opportunities to study neural activity in
unprecedented detail. Latent variable models (LVMs) are promising tools for analyzing this …