The role of Platinum (IV)-based antitumor drugs and the anticancer immune response in medicinal inorganic chemistry. A systematic review from 2017 to 2022

S Su, Y Chen, P Zhang, R Ma, W Zhang, J Liu… - European Journal of …, 2022 - Elsevier
Platinum-based antitumor drugs have been used in many types of tumors due to its broad
antitumor spectrum in clinic. Encouraged by the cisplatin's (CDDP) worldwide success in …

Nanomedicine in cancer therapy

D Fan, Y Cao, M Cao, Y Wang, Y Cao… - Signal Transduction and …, 2023 - nature.com
Cancer remains a highly lethal disease in the world. Currently, either conventional cancer
therapies or modern immunotherapies are non-tumor-targeted therapeutic approaches that …

Combinatorial photothermal 3D‐printing scaffold and checkpoint blockade inhibits growth/metastasis of breast cancer to bone and accelerates osteogenesis

C He, L Yu, H Yao, Y Chen… - Advanced Functional …, 2021 - Wiley Online Library
Cancer metastases are the main causes for the high mortality of cancer. The current
treatment modality for bone metastasis of breast cancer is dominantly destructive, which …

Esophageal cancer-derived extracellular vesicle miR-21-5p contributes to EMT of ESCC cells by disorganizing macrophage polarization

J Song, P Yang, X Li, X Zhu, M Liu, X Duan, R Liu - Cancers, 2021 - mdpi.com
Simple Summary Macrophage polarization-associated extracellular vesicles (EVs) play
crucial roles in tumor progression. The role of miR-21-5p in EVs during esophageal …

[HTML][HTML] Anti-EpCAM functionalized graphene oxide vector for tumor targeted siRNA delivery and cancer therapy

S Chen, S Zhang, Y Wang, X Yang, H Yang… - Asian journal of …, 2021 - Elsevier
Graphene oxide (GO) has emerged as a potential drug delivery vector. For siRNA delivery,
GO should be modified to endow it with gene delivery ability and targeting effect. However …

The Role of RKIP in the Regulation of EMT in the Tumor Microenvironment

H Cessna, S Baritaki, A Zaravinos, B Bonavida - Cancers, 2022 - mdpi.com
Simple Summary Raf kinase inhibitor protein (RKIP) expression in cancer cells is
significantly reduced and promoting cancer cells growth and invasiveness. Overexpresssion …

Prognostic significance of PD‐L1 expression on cell‐surface vimentin‐positive circulating tumor cells in gastric cancer patients

M Liu, R Wang, X Sun, Y Liu, Z Wang, J Yan… - Molecular …, 2020 - Wiley Online Library
Although circulating tumor cells (CTCs) have shown promise as potential biomarkers for
diagnostic and prognostic assessment in gastric cancer (GC), determining the predictive and …

Evaluation of EpCAM-specific exosomal lncRNAs as potential diagnostic biomarkers for lung cancer using droplet digital PCR

X Shen, Y Yang, Y Chen, C Zhou, X Zhao, N Li… - Journal of Molecular …, 2022 - Springer
Accumulating evidence demonstrated that long non-coding RNAs (lncRNAs) derived from
exosomes had the potential to be diagnostic markers for lung cancer. However, the …

A novel theranostic gold nanorods-and Adriamycin-loaded micelle for EpCAM targeting, laser ablation, and photoacoustic imaging of cancer stem cells in …

E Locatelli, Y Li, I Monaco, W Guo… - International Journal …, 2019 - Taylor & Francis
Introduction and purpose Cancer stem cells (CSCs) present a higher capacity to evade
being killed by cancer agents and develo** chemoresistance, thus leading to failure of …

Quantitatively map** the assembly pattern of EpCAM on cell membranes with peptide probes

Y **g, L Zhou, J Chen, H Xu, J Sun, M Cai… - Analytical …, 2019 - ACS Publications
Epithelial cell adhesion molecule (EpCAM) is an important type I transmembrane protein
that is overexpressed on the surfaces of most cancer cells and involved in various biological …