[HTML][HTML] Desaturases and elongases involved in long-chain polyunsaturated fatty acid biosynthesis in aquatic animals: From genes to functions

Ó Monroig, AC Shu-Chien, N Kabeya, DR Tocher… - Progress in lipid …, 2022 - Elsevier
Marine ecosystems are rich in “omega-3” long-chain (C 20-24) polyunsaturated fatty acids
(LC-PUFA). Their production has been historically accepted to derive mostly from marine …

Omega-3 long-chain polyunsaturated fatty acids and aquaculture in perspective

DR Tocher - Aquaculture, 2015 - Elsevier
In the 40 years since the essentiality of polyunsaturated fatty acids (PUFA) in fish was first
established by determining quantitative requirements for 18: 3n− 3 and 18: 2n− 6 in rainbow …

The future of genetic engineering to provide essential dietary nutrients and improve growth performance in aquaculture: advantages and challenges

ATY Osmond, SM Colombo - Journal of the World Aquaculture …, 2019 - Wiley Online Library
Advancements in gene technology in recent years have been driving the aquaculture
industry forward. Improvements in growth performance, feed efficiency, and omega‐3 …

[HTML][HTML] Two alternative pathways for docosahexaenoic acid (DHA, 22: 6n-3) biosynthesis are widespread among teleost fish

A Oboh, N Kabeya, G Carmona-Antoñanzas… - Scientific reports, 2017 - nature.com
Docosahexaenoic acid (DHA) plays important physiological roles in vertebrates. Studies in
rats and rainbow trout confirmed that DHA biosynthesis proceeds through the so-called …

Functional characterization and differential nutritional regulation of putative Elovl5 and Elovl4 elongases in large yellow croaker (Larimichthys crocea)

S Li, Ó Monroig, T Wang, Y Yuan, J Carlos Navarro… - Scientific reports, 2017 - nature.com
In the present study, two elongases, Elovl4 and Elovl5, were functionally characterized and
their transcriptional regulation in response to n-3 LC-PUFA administration were investigated …

Changes in the liver transcriptome of farmed Atlantic salmon (Salmo salar) fed experimental diets based on terrestrial alternatives to fish meal and fish oil

A Caballero-Solares, X Xue, CC Parrish, MB Foroutani… - BMC genomics, 2018 - Springer
Background Dependence on marine natural resources threatens the sustainability of Atlantic
salmon aquaculture. In the present study, Atlantic salmon fed for 14 weeks with an …

CRISPR/Cas9-mediated transgenesis of the masu salmon (Oncorhynchus masou) elovl2 gene improves n-3 fatty acid content in channel catfish (Ictalurus punctatus)

D **ng, B Su, S Li, M Bangs, D Creamer, M Coogan… - Marine …, 2022 - Springer
Omega-3 polyunsaturated fatty acids (n-3 PUFAs), particularly eicosapentaenoic acid (EPA,
20: 5n-3) and docosahexaenoic acid (DHA, 22: 6n-3), play a very important role in human …

Genome Manipulation Advances in Selected Aquaculture Organisms

J Wang, Y Cheng, B Su, RA Dunham - Reviews in Aquaculture, 2025 - Wiley Online Library
With the rising global demand for seafood and the challenges posed by overfishing and
climate change, the aquaculture sector has become increasingly important in providing high …

Polyunsaturated fatty acid metabolism in a marine teleost, Nibe croaker Nibea mitsukurii: Functional characterization of Fads2 desaturase and Elovl5 and Elovl4 …

N Kabeya, Y Yamamoto, SF Cummins, A Elizur… - … and Physiology Part B …, 2015 - Elsevier
To reduce the requirement for fish oil in marine aquaculture, it would be advantageous to
endow marine fish species with the capability for the endogenous biosynthesis of …

Uncommon fatty acids and cardiometabolic health

K Li, AJ Sinclair, F Zhao, D Li - Nutrients, 2018 - mdpi.com
Cardiovascular disease (CVD) is a major cause of mortality. The effects of several
unsaturated fatty acids on cardiometabolic health, such as eicosapentaenoic acid (EPA) …