Trends in insulin resistance: insights into mechanisms and therapeutic strategy

M Li, X Chi, Y Wang, S Setrerrahmane… - Signal transduction and …, 2022 - nature.com
The centenary of insulin discovery represents an important opportunity to transform diabetes
from a fatal diagnosis into a medically manageable chronic condition. Insulin is a key …

[HTML][HTML] Gestational diabetes mellitus—recent literature review

R Modzelewski, MM Stefanowicz-Rutkowska… - Journal of clinical …, 2022 - mdpi.com
Gestational diabetes mellitus (GDM), which is defined as a state of hyperglycemia that is first
recognized during pregnancy, is currently the most common medical complication in …

Application of exosomes as liquid biopsy in clinical diagnosis

B Zhou, K Xu, X Zheng, T Chen, J Wang… - Signal transduction and …, 2020 - nature.com
Liquid biopsy refers to the sampling and molecular analysis of the biofluids of circulating
tumor cells, extracellular vesicles, nucleic acids, and so forth. Exosomes are small …

A clinical update on gestational diabetes mellitus

A Sweeting, J Wong, HR Murphy, GP Ross - Endocrine reviews, 2022 - academic.oup.com
Gestational diabetes mellitus (GDM) traditionally refers to abnormal glucose tolerance with
onset or first recognition during pregnancy. GDM has long been associated with obstetric …

The pathophysiology of gestational diabetes mellitus

JF Plows, JL Stanley, PN Baker, CM Reynolds… - International journal of …, 2018 - mdpi.com
Gestational diabetes mellitus (GDM) is a serious pregnancy complication, in which women
without previously diagnosed diabetes develop chronic hyperglycemia during gestation. In …

[HTML][HTML] Role of oxidative stress and inflammation in gestational diabetes mellitus

R Saucedo, C Ortega-Camarillo, A Ferreira-Hermosillo… - Antioxidants, 2023 - mdpi.com
Gestational diabetes mellitus (GDM) is one of the most common pregnancy complications. It
is related to several gestational and fetal adverse outcomes. Moreover, women with GDM …

Placental IGFBP1 levels during early pregnancy and the risk of insulin resistance and gestational diabetes

MF Hivert, F White, C Allard, K James, S Majid… - Nature Medicine, 2024 - nature.com
Reduced insulin sensitivity (insulin resistance) is a hallmark of normal physiology in late
pregnancy and also underlies gestational diabetes mellitus (GDM). We conducted …

Determinants of maternal insulin resistance during pregnancy: an updated overview

U Kampmann, S Knorr, J Fuglsang… - Journal of diabetes …, 2019 - Wiley Online Library
Insulin resistance changes over time during pregnancy, and in the last half of the pregnancy,
insulin resistance increases considerably and can become severe, especially in women with …

The impact of diagnostic criteria for gestational diabetes on its prevalence: a systematic review and meta-analysis

S Behboudi-Gandevani, M Amiri… - Diabetology & metabolic …, 2019 - Springer
Background The absence of universal gold standards for screening of gestational diabetes
(GDM) has led to heterogeneity in the identification of GDM, thereby impacting the accurate …

Autoimmune disease in women: endocrine transition and risk across the lifespan

MK Desai, RD Brinton - Frontiers in endocrinology, 2019 - frontiersin.org
Women have a higher incidence and prevalence of autoimmune diseases than men, and
85% or more patients of multiple autoimmune diseases are female. Women undergo …