SABRE: Chemical kinetics and spin dynamics of the formation of hyperpolarization

DA Barskiy, S Knecht, AV Yurkovskaya… - Progress in Nuclear …, 2019 - Elsevier
In this review, we present the physical principles of the SABRE (Signal Amplification By
Reversible Exchange) method. SABRE is a promising hyperpolarization technique that …

Recent advances in the application of parahydrogen in catalysis and biochemistry

G Buntkowsky, F Theiss, J Lins, YA Miloslavina… - RSC …, 2022 - pubs.rsc.org
Nuclear Magnetic Resonance (NMR) spectroscopy and Magnetic Resonance Imaging (MRI)
are analytical and diagnostic tools that are essential for a very broad field of applications …

In Situ Hyperpolarization Enables 15N and 13C Benchtop NMR at Natural Isotopic Abundance

R Kircher, J Xu, DA Barskiy - Journal of the American Chemical …, 2023 - ACS Publications
Without employing isotopic labeling, we demonstrate the generation of 15N and 13C NMR
signals for molecules containing− NH2 motifs using benchtop NMR spectrometers (1–1.4 T) …

Parahydrogen-based NMR signal amplification by reversible exchange (SABRE): Recent advances and applications

OG Salnikov, DB Burueva, IV Skovpin… - Mendeleev …, 2023 - Elsevier
Signal amplification by reversible exchange (SABRE) is a rapidly develo** nuclear
magnetic resonance (NMR) hyperpolarization technique utilizing parahydrogen for dramatic …

Metal-Mediated Catalytic Polarization Transfer from para Hydrogen to 3,5-Dihalogenated Pyridines

BJ Tickner, M Dennington, BG Collins, CA Gater… - ACS …, 2024 - ACS Publications
The neutral catalysts [IrCl (H) 2 (NHC)(substrate) 2] or [IrCl (H) 2 (NHC)(substrate)(sulfoxide)
] are used to transfer polarization from para hydrogen (p H2) to 3, 5-dichloropyridine and 3, 5 …

SABRE Hyperpolarization with up to 200 bar Parahydrogen in Standard and Quickly Removable Solvents

A Duchowny, J Denninger, L Lohmann, T Theis… - International Journal of …, 2023 - mdpi.com
Para hydrogen (p-H2)-based techniques are known to drastically enhance NMR signals but
are usually limited by p-H2 supply. This work reports p-H2-based SABRE hyperpolarization …

[HTML][HTML] Low-frequency excitation of singlet–triplet transitions. Application to nuclear hyperpolarization

L Dagys, C Bengs, MH Levitt - The Journal of Chemical Physics, 2021 - pubs.aip.org
Coupled pairs of nuclear spin-1/2 support one singlet state and three triplet states.
Transitions between the singlet state and one of the triplet states may be driven by an …

Advancing homogeneous catalysis for parahydrogen-derived hyperpolarisation and its NMR applications

BJ Tickner, VV Zhivonitko - Chemical science, 2022 - pubs.rsc.org
Parahydrogen-induced polarisation (PHIP) is a nuclear spin hyperpolarisation technique
employed to enhance NMR signals for a wide range of molecules. This is achieved by …

Solvent Effects in Hyperpolarization of 15N Nuclei in [15N3]Metronidazole and [15N3]Nimorazole Antibiotics via SABRE‐SHEATH**

AP Yi, OG Salnikov, DB Burueva… - Analysis & …, 2024 - Wiley Online Library
Metronidazole and nimorazole are antibiotics of a nitroimidazole group which also may be
potentially utilized as hypoxia radiosensitizers for the treatment of cancerous tumors …

Enhancing the NMR signals of plant oil components using hyperpolarisation relayed via proton exchange

A Alshehri, BJ Tickner, W Iali, SB Duckett - Chemical Science, 2023 - pubs.rsc.org
In this work, the limited sensitivity of magnetic resonance is addressed by using the
hyperpolarisation method relayed signal amplification by reversible exchange (SABRE …