Rethinking drug design in the artificial intelligence era
Artificial intelligence (AI) tools are increasingly being applied in drug discovery. While some
protagonists point to vast opportunities potentially offered by such tools, others remain …
protagonists point to vast opportunities potentially offered by such tools, others remain …
Industrial information integration—A literature review 2006–2015
Y Chen - Journal of industrial information integration, 2016 - Elsevier
In the last few years, Industrial Information Integration Engineering (IIIE) has attracted much
attention by the information and communications technology (ICT) community. However …
attention by the information and communications technology (ICT) community. However …
[LIBRO][B] Designing and building enterprise knowledge graphs
This book is a guide to designing and building knowledge graphs from enterprise relational
databases in practice.\It presents a principled framework centered on map** patterns to …
databases in practice.\It presents a principled framework centered on map** patterns to …
Big data in drug discovery
Abstract Interpretation of Big Data in the drug discovery community should enhance project
timelines and reduce clinical attrition through improved early decision making. The issues …
timelines and reduce clinical attrition through improved early decision making. The issues …
Evolving BioAssay Ontology (BAO): modularization, integration and applications
The lack of established standards to describe and annotate biological assays and screening
outcomes in the domain of drug and chemical probe discovery is a severe limitation to utilize …
outcomes in the domain of drug and chemical probe discovery is a severe limitation to utilize …
API-centric linked data integration: The open PHACTS discovery platform case study
Data integration is a key challenge faced in pharmacology where there are numerous
heterogeneous databases spanning multiple domains (eg chemistry and biology). To …
heterogeneous databases spanning multiple domains (eg chemistry and biology). To …
Evidence-based and quantitative prioritization of tool compounds in phenotypic drug discovery
The use of potent and selective chemical tools with well-defined targets can help elucidate
biological processes driving phenotypes in phenotypic screens. However, identification of …
biological processes driving phenotypes in phenotypic screens. However, identification of …
Ten simple rules for selecting a bio-ontology
Biologists and bioinformaticians now look to ontologies or software that uses ontologies as a
means of standardising the way data are described, queried, and interpreted. Ontologies …
means of standardising the way data are described, queried, and interpreted. Ontologies …
A pay-as-you-go methodology to design and build enterprise knowledge graphs from relational databases
Business users must answer business questions quickly to address Business Intelligence
(BI) needs. The bottleneck is to understand the complex databases schemas. Only few …
(BI) needs. The bottleneck is to understand the complex databases schemas. Only few …
Construction of a knowledge graph for diabetes complications from expert-reviewed clinical evidences
L Wang, H **e, W Han, X Yang, L Shi… - Computer Assisted …, 2020 - Taylor & Francis
A knowledge graph is a structured representation of data that can express entity and
relational knowledge. More attention has been paid to the study of a clinical knowledge …
relational knowledge. More attention has been paid to the study of a clinical knowledge …