[HTML][HTML] The role of different viral biomarkers on the management of chronic hepatitis B

LY Mak, RWH Hui, J Fung, WK Seto… - Clinical and Molecular …, 2023 - ncbi.nlm.nih.gov
Chronic hepatitis B infection is a major public health challenge. With the advancement in
technology, various components of the viral cycle can now be measured in the blood to …

Effects of hepatitis B virus infection and strategies for preventing mother-to-child transmission on maternal and fetal T-cell immunity

H Lu, W Cao, L Zhang, L Yang, X Bi, Y Lin… - Frontiers in …, 2023 - frontiersin.org
One of the most common routes of chronic hepatitis B virus (HBV) infection is mother-to-child
transmission (MTCT). Approximately 6.4 million children under the age of five have chronic …

A risk prediction model for hepatocellular carcinoma after hepatitis B surface antigen seroclearance

H Yang, SH Bae, H Nam, HL Lee, SW Lee, SH Yoo… - Journal of …, 2022 - Elsevier
Background & Aims After hepatitis B surface antigen (HBsAg) seroclearance, the risk of
hepatocellular carcinoma (HCC) remains, and the optimal surveillance strategy has yet to be …

Outcome of untreated low-level viremia versus antiviral therapy-induced or spontaneous undetectable HBV-DNA in compensated cirrhosis

DQ Huang, N Tamaki, HW Lee, SY Park, YR Lee… - Hepatology, 2023 - journals.lww.com
Background: Comparative outcomes of HBV-infected compensated cirrhosis with low-level
viremia (LLV) versus maintained virological response (MVR) are unclear. We conducted a …

Reduction in intrahepatic cccDNA and integration of HBV in chronic hepatitis B patients with a functional cure

W Gan, N Gao, L Gu, Z Mo, X Pang… - Journal of clinical and …, 2022 - pmc.ncbi.nlm.nih.gov
Background and Aims Functional cure (FC) is characterized by the clearance of the hepatitis
B surface antigen from the serum of patients with chronic hepatitis B (CHB). However, the …

A longitudinal study to detect hepatitis B surface and core-related antigens in chronic hepatitis B patients with hepatitis B surface antigen seroclearance using highly …

DKH Wong, T Inoue, LY Mak, RWH Hui, J Fung… - Journal of Clinical …, 2023 - Elsevier
Background This study aimed to evaluate the usefulness of two novel assays, namely the
iTACT-hepatitis B surface antigen (iTACT-HBsAg) and iTACT-hepatitis B core-related …

Comparable outcomes between immune-tolerant and active phases in noncirrhotic chronic hepatitis B: a meta-analysis

HA Lee, SU Kim, YS Seo, SH Ahn… - Hepatology …, 2023 - journals.lww.com
Background: Antiviral therapy is not indicated for patients with chronic hepatitis B (CHB) in
the immune-tolerant (IT) phase. We compared the outcomes between the untreated IT phase …

Hepatitis B virus DNA integration as a novel biomarker of hepatitis B virus-mediated pathogenetic properties and a barrier to the current strategies for hepatitis B virus …

R Salpini, S D'Anna, L Benedetti, L Piermatteo… - Frontiers in …, 2022 - frontiersin.org
Chronic infection with Hepatitis B Virus (HBV) is a major cause of liver-related morbidity and
mortality worldwide. HBV-DNA integration into the human genome is recognized as a …

Distinct Patterns of HBV Integration and TERT Alterations between in Tumor and Non-Tumor Tissue in Patients with Hepatocellular Carcinoma

JW Jang, HS Kim, JS Kim, SK Lee, JW Han… - International journal of …, 2021 - mdpi.com
Although hepatitis B virus (HBV) integration into the cellular genome is well known in HCC
(hepatocellular carcinoma) patients, its biological role still remains uncertain. This study …

[HTML][HTML] KASL clinical practice guidelines for management of chronic hepatitis B

Korean Association for the Study of the … - Clinical and …, 2022 - ncbi.nlm.nih.gov
Chronic hepatitis B (CHB) is a major cause of chronic liver diseases in Korea and remains a
threat to public health due to its high morbidity and disease-related mortality. Since the latest …