Nanomedicines based on poly (lactic-co-glycolic acid)(PLGA) carriers offer tremendous
opportunities for biomedical research. Although several PLGA-based systems have already …

Diabetes mellitus (DM) is a collection of metabolic and pathophysiological disorders
manifested with high glucose levels in the blood due to the inability of β-pancreatic cells to …

Nucleolin or C23, is one of the most abundant non-ribosomal phosphoproteins of nucleolus.
However, in several cancers, nucleolin is highly expressed both intracellularly and on the …

Using nanoparticles to carry and delivery anticancer drugs holds much promise in cancer
therapy, but nanoparticles per se are lacking specificity. Active targeting, that is, using …

Polymeric biomaterials have found widespread applications in nanomedicine, and poly
(lactide-co-glycolide),(PLGA) in particular has been successfully implemented in numerous …

Aptamers have come in the spotlight as bio-mimetic molecular recognition elements in the
field of biomedicine due to various applications in diagnostics, drug delivery, therapeutics …

Doxorubicin (DOX) is a natural antibiotic with antineoplastic activity. It has been used for
over 40 years and remains one of the most used drugs in chemotherapy for a variety of …

Targeted therapy is highly desirable, as it allows for selective cytotoxicity on diseased cells
without off-target side effects. Nucleolin is a remarkable target for cancer therapy given its …

Breast carcinoma is a molecularly diverse illness, and it is among the most prominent and
often reported malignancies in female across the globe. Surgical intervention …

Most problems associated with chemotherapeutic agents involve non-specific cytotoxicity,
low intratumoral accumulation and drug resistance. Targeted drug delivery systems (TDDS) …