Pathogenesis of respiratory viral and fungal coinfections

F Salazar, E Bignell, GD Brown, PC Cook… - Clinical Microbiology …, 2022 - journals.asm.org
Individuals suffering from severe viral respiratory tract infections have recently emerged as
“at risk” groups for develo** invasive fungal infections. Influenza virus is one of the most …

Immune defence against Candida fungal infections

MG Netea, LAB Joosten, JWM Van Der Meer… - Nature Reviews …, 2015 - nature.com
The immune response to Candida species is shaped by the commensal character of the
fungus. There is a crucial role for discerning between colonization and invasion at mucosal …

Pathogenicity and virulence of Aspergillus fumigatus

K Earle, C Valero, DP Conn, G Vere, PC Cook… - Virulence, 2023 - Taylor & Francis
Pulmonary infections caused by the mould pathogen Aspergillus fumigatus are a major
cause of morbidity and mortality globally. Compromised lung defences arising from …

Risk stratification for invasive fungal infections in patients with hematological malignancies: SEIFEM recommendations

L Pagano, A Busca, A Candoni, C Cattaneo, S Cesaro… - Blood reviews, 2017 - Elsevier
Invasive fungal infections (IFIs) are an important cause of morbidity and mortality in
immunocompromised patients. Patients with hematological malignancies undergoing …

[HTML][HTML] Prevalence of COVID-19-associated pulmonary aspergillosis: critical review and conclusions

M Egger, L Bussini, M Hoenigl, M Bartoletti - Journal of Fungi, 2022 - mdpi.com
First reports of cases and case series of COVID-19-associated pulmonary aspergillosis
(CAPA) emerged during the first months of the pandemic. Prevalence rates varied widely …

Host response to Candida albicans bloodstream infection and sepsis

S Duggan, I Leonhardt, K Hünniger, O Kurzai - Virulence, 2015 - Taylor & Francis
Candida albicans is a major cause of bloodstream infection which may present as sepsis
and septic shock-major causes of morbidity and mortality world-wide. After invasion of the …

Omalizumab is effective in symptomatic dermographism—results of a randomized placebo-controlled trial

M Maurer, A Schütz, K Weller, N Schoepke… - Journal of Allergy and …, 2017 - jacionline.org
The trial was an investigator-initiated trial funded, in part, by Novartis and by an intramural
grant. Novartis had no role in the study design, the collection, analysis, and interpretation of …

Genomic and phenotypic trait variation of the opportunistic human pathogen Aspergillus flavus and its close relatives

EA Hatmaker, M Rangel-Grimaldo, HA Raja… - Microbiology …, 2022 - journals.asm.org
Fungal diseases affect millions of humans annually, yet fungal pathogens remain
understudied. The mold Aspergillus flavus can cause both aspergillosis and fungal keratitis …

Immune correlates of protection in human invasive aspergillosis

JF Camargo, S Husain - Clinical infectious diseases, 2014 - academic.oup.com
An improved understanding of the pathogenesis of Aspergillus infections has facilitated the
identification of host biomarkers that, if validated in well-designed prospective studies, could …

Preparations for Invasion: Modulation of Host Lung Immunity During Pulmonary Aspergillosis by Gliotoxin and Other Fungal Secondary Metabolites

M Arias, L Santiago, M Vidal-García… - Frontiers in …, 2018 - frontiersin.org
Pulmonary aspergillosis is a severe infectious disease caused by some members of the
Aspergillus genus, that affects immunocompetent as well as immunocompromised patients …