Turnitin
降AI改写
早检测系统
早降重系统
Turnitin-UK版
万方检测-期刊版
维普编辑部版
Grammarly检测
Paperpass检测
checkpass检测
PaperYY检测
Clozapine haematological monitoring for neutropenia: a global perspective
AimsClozapine is licensed for treatment-resistant psychosis and remains underutilised. This
may berelated to the stringent haematological monitoring requirements that are mandatory …
may berelated to the stringent haematological monitoring requirements that are mandatory …
Risks and benefits of clozapine and lithium co-prescribing: a systematic review and expert recommendations
Objectives To identify the risks and benefits of clozapine‑lithium co-prescription. Methods
Articles published in English or French were identified with a MEDLINE, Web of Sciences …
Articles published in English or French were identified with a MEDLINE, Web of Sciences …
A population pharmacokinetic model to guide clozapine dose selection, based on age, sex, ethnicity, body weight and smoking status
Aims Guidance on clozapine dosing in treatment‐resistant schizophrenia is based largely
on data from White young adult males. This study aimed to investigate the pharmacokinetic …
on data from White young adult males. This study aimed to investigate the pharmacokinetic …
[HTML][HTML] Slower clozapine titration than the official Japanese protocol led to fewer inflammatory adverse effects: a retrospective chart review of seven hospitals
Y Kikuchi, H Komatsu, Y Otsuka, F Ito, N Kanahara… - Schizophrenia …, 2024 - Elsevier
Background Higher frequencies of inflammatory adverse effects of clozapine have been
reported in Japan. As the international titration protocol for Asians has set slower dose …
reported in Japan. As the international titration protocol for Asians has set slower dose …
Risk of clozapine-associated agranulocytosis and mandatory white blood cell monitoring: Can the regulations be relaxed?
PFJ Schulte, SRT Veerman, B Bakker… - Schizophrenia …, 2024 - Elsevier
After the introduction of clozapine eight Finnish patients died after develo**
agranulocytosis. Clozapine was withdrawn from the market and only reintroduced with strict …
agranulocytosis. Clozapine was withdrawn from the market and only reintroduced with strict …
Second to none: rationale, timing, and clinical management of clozapine use in schizophrenia
Despite its enduring relevance as the single most effective and important evidence-based
treatment for schizophrenia, underutilization of clozapine remains considerable. To a …
treatment for schizophrenia, underutilization of clozapine remains considerable. To a …
Clinical impact of reducing the frequency of clozapine monitoring: controlled mirror-image cohort study
BackgroundTo minimise infection during COVID-19, the clozapine haematological
monitoring interval was extended from 4-weekly to 12-weekly intervals in South London and …
monitoring interval was extended from 4-weekly to 12-weekly intervals in South London and …
The lived experience of clozapine discontinuation in patients and carers following suspected clozapine-induced neutropenia
Background Clozapine is the treatment of choice in refractory psychosis. In most countries,
clozapine must be stopped indefinitely if white blood cells fall below a defined threshold …
clozapine must be stopped indefinitely if white blood cells fall below a defined threshold …
International variation in clozapine hematologic monitoring—a call for action
Clozapine Clozapine was first synthesized in the 1950s but remains the only licensed
medication for treatmentresistant psychosis. 1 Treatment-resistant psychosis, defined as the …
medication for treatmentresistant psychosis. 1 Treatment-resistant psychosis, defined as the …
Understanding clozapine-related blood dyscrasias. Developments, genetics, ethnicity and disparity: it's a CIN
Clozapine remains the gold standard intervention for treatment-resistant schizophrenia;
however, it remains underused, especially for some minority groups. A significant …
however, it remains underused, especially for some minority groups. A significant …