The association between adverse childhood experiences and late-life cognition: a systematic review of cross-sectional and case-control studies

P Patel, M Oremus - The Gerontologist, 2023 - academic.oup.com
Abstract Background and Objectives Adverse childhood experiences (ACEs) are a
recognized risk factor for unfavorable health outcomes. No prior systematic review has …

Early-life stress lastingly impacts microglial transcriptome and function under basal and immune-challenged conditions

K Reemst, L Kracht, JM Kotah, R Rahimian… - Translational …, 2022 - nature.com
Early-life stress (ELS) leads to increased vulnerability to psychiatric disorders including
depression later in life. Neuroinflammatory processes have been implicated in ELS-induced …

Association of childhood trauma with cognitive domains in adult patients with mental disorders and in non-clinical populations: a systematic review

M Rosa, C Scassellati, A Cattaneo - Frontiers in psychology, 2023 - frontiersin.org
Although the association between cognitive performances and the onset of psychiatric
disorders has been widely investigated, limited research on the role of childhood trauma or …

Examining biopsychosocial predictors of risk for cognitive impairment among a racially diverse sample of men who have sex with men living with HIV

CD Xavier Hall, B Okantey, Z Meng… - Therapeutic …, 2024 - journals.sagepub.com
Background: Cognitive decline among people living with HIV (PLWH) is growing concern as
world populations become increasing older including higher proportions of PLWH. It is vitally …

Adverse childhood experiences and aging-associated functional impairment in a national sample of older community-dwelling adults

VM Lee, AS Hargrave, NE Lisha, AJ Huang - Journal of General Internal …, 2023 - Springer
Background Prior research on the health implications of adverse childhood experiences
(ACEs) has focused on early or midlife adults, not older adults who bear the greatest burden …

Midlife financial stress and cognitive and physical impairments in older age: The role of potentially modifying factors

I Kåreholt, C Nilsen, M Kivipelto, D Finkel… - Social Science & …, 2025 - Elsevier
Background Financial stress is an important source of chronic stress and has been
associated with cognitive and physical impairments. The goal of this study was to investigate …

Addressing the biological embedding of early life adversities (ELA) among adults through mindfulness: Proposed mechanisms and review of converging evidence

S Sun, MA Sheridan, AR Tyrka, SD Donofry… - Neuroscience & …, 2022 - Elsevier
Early life adversities (ELA) are prevalent and have a profound and adverse impact across
the lifespan, including on age-related health outcomes, yet interventions to remediate its …

[HTML][HTML] Effect of childhood trauma on cognitive function in individuals with major depressive disorder and healthy controls

F Cui, Q Liu, X Lv, H Tian, J Wei, K Zhang, G Zhu… - Journal of Affective …, 2025 - Elsevier
Background Individuals with major depressive disorder (MDD) exhibit cognitive impairment,
while childhood trauma (CT) is associated with an elevated risk of both MDD and cognitive …

Disparities in the Life Course Origins of Dual Functionality

KF Ferraro, MR Sauerteig-Rolston… - Journal of Health …, 2024 - journals.sagepub.com
Although research has identified how stressors are related to either physical or cognitive
function in later life, we bridge these literatures by examining dual functionality (neither …