Abstract Coronavirus disease 2019 (COVID-19) and its causative virus, SARS-CoV-2, pose
considerable challenges for the management of oncology patients. COVID-19 presents as a …

Gene mutations are strongly associated with tumor progression and are well known in
cancer development. However, recently discovered epigenetic alterations have shown the …

The critical role of dysregulated epigenetic pathways in cancer genesis, development, and
therapy has typically been established as a result of scientific and technical innovations in …

Atypical teratoid rhabdoid tumors (AT/RT) are malignant central nervous system (CNS)
tumors that occur mostly in young children and have historically carried a very poor …

The growing cost of medical care worldwide, particularly in oncology, has incentivized
researchers and physicians to repurpose clinically used drugs to alleviate the financial …

Epigenetic alterations, as a cancer hallmark, are associated with cancer initiation,
progression and aggressiveness. Considering, however, that these alterations are …

Atypical teratoid rhabdoid tumor (ATRT) is a rare, highly malignant central nervous system
cancer arising in infants and younger children, historically considered to be homogeneous …

Nasopharyngeal carcinoma (NPC) is a squamous cell carcinoma with a proclivity for
systemic dissemination, leading many patients to present with advanced stage disease and …

OBJECTIVE Medulloblastoma, the most common pediatric brain malignancy, has Sonic
Hedgehog (SHH) and group 3 (Myc driven) subtypes that are associated with the activity of …

The prognosis of gioblastoma, the standard chemotherapy agent for which is temozolomide
(TMZ), remains poor despite recent advances in multimodal treatments. Therefore, it is …