[HTML][HTML] FOSL1 promotes cholangiocarcinoma via transcriptional effectors that could be therapeutically targeted

A Vallejo, O Erice, R Entrialgo-Cadierno, I Feliu… - Journal of …, 2021 - Elsevier
Background & Aims Cholangiocarcinoma (CCA) is a neoplasia of the biliary tract driven by
genetic, epigenetic and transcriptional mechanisms. Herein, we investigated the role of the …

PTEN deficiency induces an extrahepatic cholangitis-cholangiocarcinoma continuum via aurora kinase A in mice

Y Yang, J Wang, J Wan, Q Cheng, Z Cheng, X Zhou… - Journal of …, 2024 - Elsevier
Background & Aims The PTEN-AKT pathway is frequently altered in extrahepatic
cholangiocarcinoma (eCCA). We aimed to evaluate the role of PTEN in the pathogenesis of …

Pharmacological inhibition of Protein kinase D2/Aurora kinase A signalling axis suppresses G2/M cell cycle progression and proliferation of epithelial ovarian cancer …

A Sachdeva, A Roy, MK Gupta, S Mandal - Pathology-Research and …, 2024 - Elsevier
Epithelial ovarian cancer (EOC) is the deadliest gynecological malignancy with poor
prognosis and patient survival outcome. Protein kinase D2 (PKD2) belongs to …

Identification of Hub Genes and Pathways With Immune Cell Infiltration in Cholangiocarcinoma by Weighted Gene Co-expression Network Analysis

Y Yan, L Zhao, H Su, G Li, S Jiang - 2020 - researchsquare.com
Background: Cholangiocarcinoma (CCA) is the most frequent tumor in biliary tract and the
second most common primary tumor of the liver. However, the molecular biomarkers in …