Advances in the early detection of hepatobiliary cancers
Simple Summary Hepatocellular cancer and biliary tract cancers are associated with poor
prognosis, particularly in advanced stages. However, early diagnosis offers the potential for …
prognosis, particularly in advanced stages. However, early diagnosis offers the potential for …
[HTML][HTML] Recent advances in the management of primary sclerosing cholangitis
DN Assis, CL Bowlus - Clinical Gastroenterology and Hepatology, 2023 - Elsevier
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by
fibroinflammatory damage to the biliary tree, typically in the setting of inflammatory bowel …
fibroinflammatory damage to the biliary tree, typically in the setting of inflammatory bowel …
Immunobiology of primary sclerosing cholangitis
Primary sclerosing cholangitis (PSC) is a chronic inflammatory progressive cholestatic liver
disease. Genetic risk factors, presence of autoantibodies, the strong clinical link with …
disease. Genetic risk factors, presence of autoantibodies, the strong clinical link with …
[HTML][HTML] Prognostic models and autoimmune liver diseases
D D'Amato, M Carbone - Best Practice & Research Clinical …, 2023 - Elsevier
Autoimmune liver diseases (AILDs) are complex diseases with unknown causes and
immune-mediated pathophysiology. In primary biliary cholangitis (PBC) and autoimmune …
immune-mediated pathophysiology. In primary biliary cholangitis (PBC) and autoimmune …
[HTML][HTML] Primary Sclerosing Cholangitis-Associated Cholangiocarcinoma: From Pathogenesis to Diagnostic and Surveillance Strategies
E Catanzaro, E Gringeri, P Burra, M Gambato - Cancers, 2023 - mdpi.com
Cholangiocarcinoma (CCA) is the most common malignancy in patients with primary
sclerosing cholangitis (PSC), accounting for 2–8% of cases and being the leading cause of …
sclerosing cholangitis (PSC), accounting for 2–8% of cases and being the leading cause of …
Diagnosis of functional strictures in patients with primary sclerosing cholangitis using hepatobiliary contrast-enhanced MRI: a proof-of-concept study
S Poetter-Lang, A Messner, N Bastati, KI Ringe… - European …, 2023 - Springer
Objectives PSC strictures are routinely diagnosed on T2-MRCP as dominant-(DS) or high-
grade stricture (HGS). However, high inter-observer variability limits their utility. We …
grade stricture (HGS). However, high inter-observer variability limits their utility. We …
ZNF460-mediated upregulation of APCDD1L-DT promotes cholangiocarcinoma development by inhibiting the ubiquitin-mediated degradation of DVL2
X Gao, X Zou, C Guan, X Sha, S Liu, X Zhang… - Cancer Gene …, 2024 - nature.com
Cholangiocarcinoma (CCA), known for its aggressive nature, poses a formidable challenge
in the current medical landscape, particularly in targeted therapies. Against this backdrop …
in the current medical landscape, particularly in targeted therapies. Against this backdrop …
[HTML][HTML] The Swedish initiative for the study of Primary sclerosing cholangitis (SUPRIM)
Background Despite more than 50 years of research and parallel improvements in
hepatology and oncology, there is still today neither a treatment to prevent disease …
hepatology and oncology, there is still today neither a treatment to prevent disease …
Fluorescent Chemo sensor nano-materials for Cancer bio-markers signalling: Towards development of non-invasive early detection strategies
MS Ngigi - Dyes and Pigments, 2023 - Elsevier
Although current cancer treatment technologies have advanced quickly, the patient's chance
of recovering is still poor. Early detection enhances cancer prognosis and can considerably …
of recovering is still poor. Early detection enhances cancer prognosis and can considerably …
Risk Assessment and Cholangiocarcinoma: Diagnostic Management and Artificial Intelligence
Simple Summary The only curative treatment for intrahepatic cholangiocarcinoma (iCCA) is
surgical resection, and an early diagnosis is the most effective way to improve survival. In …
surgical resection, and an early diagnosis is the most effective way to improve survival. In …